Synthesis and antibiotic potential of myxocoumarin-inspired chromene dione analogs.

The rapid emergence of antibiotic resistance in recent years poses a substantial global health threat. Thus, the discovery of potent novel antibiotics is of utmost importance. One such compound class with promising antibiotic potential are the myxocoumarins from MYX-030, which exhibit exceptional antibiotic activities against several Gram-positive pathogens, including MRSA.