This study aimed to test the hypothesis that the postactivation effect (PAE, involuntary normal muscle tone) is modified by dopaminergic mechanisms. The PAE was tested with surface electromyography (sEMG) in the "off medication" phase in participants with Parkinson's disease (PD) and in the "on medication" state in participants with schizophrenia (SZ), which modeled hypodopaminegic conditions, and in participants with PD "on medication" (PD) and in participants with SZ "off medication" (SZ) state which modeled the hyperdopaminergic conditions. Healthy age-matched participants constituted the control group (HC, = 11).
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
August 2022
Objective: To evaluate the effectiveness of the effect of celecoxib and the combined vitamin complex of group B in comparison with meloxicam in patients with acute and chronic nonspecific lumbar pain (LP).
Material And Methods: The effectiveness of the effect on acute (44%; acute pain syndrome (APS)) and chronic (56%; chronic pain syndrome (CPS)) LP of moderate intensity (according to VAS/MPQ) (APS 5.7±2.
Zh Nevrol Psikhiatr Im S S Korsakova
April 2016
Objective: To study the efficacy and tolerability of agomelatine (valdoxan) in treatment of mild depressive states in patients with chronic brain ischemia (CBI).
Material And Methods: The study comprised 33 patients (23 women, 10 men, average age 54.5 years), including 12 people (36.
During the epidemiological survey of the military men of the Republic of Karelia with the pre-existing initial manifestations of cerebral circulation insufficiency were established it's main etiological reasons (somatoform autonomic dysfunction--35.2%, cervical osteochondrosis--34.3%) and risk factors (hereditary tainted cardiovascular event, north climate, stress, social habits, peculiarities of military service).
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
March 1997
The presented investigation was designed to elucidate whether age impacts the basic neurophysiological characteristics of motor unit (MU) thermoregulatory activity in human subjects. Human newborns and infants (aged from 7 days to 3 years, n = 81) were exposed to ambient temperatures of 26-27 degrees C for 5-7 minutes. The adults and elderly (18-76 years old, n = 90) were exposed to 10 degrees C for 30-60 minutes.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
May 1994
The correlation between the motor units activity patterns and clinical forms of parkinsonism has been investigated by means of surface electromyography. Grouped electromyogram, characteristic of parkinsonism shaking was found to be generated on the basis of double, triple discharges of the motor unit (doublets and triplets), or long-term synchronization of motor units discharges as well as by means of simultaneous recruitment of both above mechanisms. Stationary electromyogram, characteristic of akinetic-rigid form, was shown to correlate with asynchronous, stable activity of the motor units that impulse at the frequencies 9-10 Hz.
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