Intrawound navigation for custom-made acetabular component in revision total hip arthroplasty: Does it improve implant positioning?

Background: The number of hip revisions makes up over 12 % of all hip arthroplasty cases. For large acetabular defects custom-made acetabular component (CMAC) are required. Rates of malposition of CMACs are highly variable.

Safety and Immunogenicity of Betuvax-CoV-2, an RBD-Fc-Based SARS-CoV-2 Recombinant Vaccine: Preliminary Results of the First-in-Human, Randomized, Double-Blind, Placebo-Controlled Phase I/II Clinical Trial.

Unlabelled: COVID-19, being a life-threatening infection that evolves rapidly, remains a major public health concern calling for the development of vaccines with broad protection against different pathogenic strains and high immunogenicity. Aside from this, other concerns in mass immunization settings are also the scalability of production and relative affordability of the technology. In that regard, adjuvanted protein vaccines with particles mimicking the virus stand out among known vaccine technologies.

Standard Versus Custom-Made Acetabular Implants in Revision Total Hip Arthroplasty.

Background: Today, various options are used for the reconstruction of acetabular bone loss in revision total hip arthroplasty (RTHA). The aim of the study was to compare the outcomes of using standard acetabular implants (SAIs) and custom-made acetabular implants (CMAIs) in RTHA in cases with extensive acetabular bone loss.

Methods: This was a comparative analysis of the results of 106 operations of RTHA performed during the period from January 2013 to December 2019.

A prospective study on outcome of patient-specific cones in revision knee arthroplasty.

Background: Cones are known to be good substitutes for metaphyseal and diaphyseal bone loss during revision total knee arthroplasty (RTKA). Often the off-the-shelf cones do not fit to the individual patient's anatomy. New 3D-printing additive technologies allow to develop patient-specific cones.

Fibrin Glue Implants Seeded with Dental Pulp and Periodontal Ligament Stem Cells for the Repair of Periodontal Bone Defects: A Preclinical Study.

A technology to create a cell-seeded fibrin-based implant matching the size and shape of bone defect is required to create an anatomical implant. The aim of the study was to develop a technology of cell-seeded fibrin gel implant creation that has the same shape and size as the bone defect at the site of implantation. Using computed tomography (CT) images, molds representing bone defects were created by 3D printing.

Redox and complexation interactions of neptunium(V) with quinonoid-enriched humic derivatives.

Actinides in their higher valence states (e.g., MO2+ and MO2(2+), where M can be Np, Pu, etc) possess a higher potential for migration and in turn pose a substantial environmental threat.

Design of quinonoid-enriched humic materials with enhanced redox properties.

The primary goal of this work was to develop quinonoid-enriched humic materials with enhanced redox properties that could be used as potentially effective redox mediators and reducing agents for in situ remediation of soil and aquatic environments. Two different strategies were formulated and tested to derive these materials. The first strategy called for the oxidation of phenolic fragments associated with the humic aromatic core.