[Time perspective perception specific and maladaptation in elderly under uncertainty conditions during pandemic emergency.].

The purpose of the study - to determine the specifics of experiencing psychological stress, the time perspective and symptoms of adaptation disorders in older people in a pandemic emergency compared to the active adult population. At the first stage, 587 people were examined using the PSM-25 scale, then 100 respondents with maladaptive stress levels (sum ≥155 points) were selected. The main group consisted of 50 people aged 60 to 74 years (average age 65±2,7 years), 50 people aged 18 to 44 years (average age 32±3,8 years) were included in comparison group, who were examined with using the SCL-90-R questionnaire for assessing psychopathological symptoms and the ZTPI questionnaire for assessing the perception of time perspective.

[Clinical features of asthenia in the context of adjustment disorders].

Objective: To study asthenic symptoms in patients with adjustment disorders and to assess the efficacy of cytoflavin in their treatment.

Material And Methods: The study included 100 patients, aged 20 to 43 years, with a diagnosis of adjustment disorder. Clinical, neurophysiological and parametric methods were used.

[Cognitive control impairment in adult with attention deficit/hyperactivity disorder].

Aim: To study cognitive impairment in adults with attention deficit hyperactivity disorder (ADHD) and assess the efficacy of cerebrolysin in the treatment of such patients.

Material And Methods: Thirty-eight patients with ADHD, aged from 18 to 45 years were enrolled in the study. Along with general neurological examination, several ADHA-specific scales and tests (ASRS-V1-1, SFQ, BIS, the Emotional Intelligence Self-Evaluation, TOVA) were administered.

[The differences in the estimation of depression severity by psychiatrists and patients during the combined treatment with agomelatine (a multicenter study "EMOTSIA")].

Aim: To compare the prognosis of depression severity estimated by the physician and by the patient based on the treatment outcome.

Material And Methods: One hundred and seven patients with depression were examined. Mental status was assessed with HАМ-D, SHAPS, CGI-S, CGI-I, PGI-S, PGI-I and VAS.

[Between depression and fibroniyalgia: the fate of the antidepressant].

The authors present the information about one of the least studied antidepressants- milnacipran. Recommendations of its clinical use have been long based on incorrect conceptions of its pharmacological properties. Currently, milnacipran is considered as ancirepinephrine and serotonin (to a lesser degree) reuptake inhibitor and NMDA receptor blocker.

[Pharmacotherapy and dementia].

The review considers treatment aspects of dementia in Alzheimer's disease (DAD), vascular dementia (VD) and some other forms of dementia. Pathogenetic pharmacotherapy of DAD aims to maintain the activity of cholinergic neurons with anticholinesterase drugs including donepezil, which is used most often. The main objective of VD treatment is prevention of new cerebral infarctions using cardiotropic medications, antiaggregants, anticoagulants, hypotensive drugs and statins.

Commissioning of the accelerator-recuperator for the FEL at the Siberian Center for Photochemical Research.

A 100 MeV eight-turn accelerator-recuperator intended to drive a high-power infrared free-electron laser (FEL) is currently under construction in Novosibirsk. The first stage of the machine includes a one-turn accelerator-recuperator that contains a full-scale RF system. It was commissioned successfully in June 2002.

[Use of glurenorm in patients with non-insulin-dependent diabetes mellitus and liver diseases].

Due to its pharmacokinetics, glurenorm (95% of the drug metabolite is withdrawn from the body with the bile) is widely used in patients with non-insulin-dependent diabetes mellitus (NIDDM) with disturbed renal function. It seemed that, bearing in mind the relationship between glurenorm elimination and liver function, this drug use in patients with NIDDM patients with liver diseases should be restricted. The aim of the present research was to study glurenorm effect on liver function.

[Correlations between the pharmacokinetic indices of the tranquilizer fenazepam in single and long-term administration to patients].

A high degree of correlation between experimentally established and theoretically calculated constant concentrations of phenazepam was revealed in blood plasma of patients. Due to experimental findings the employment of a single-dose drug administration with regard to previously stated effective-dose interval during dosage build-up made possible estimating the maximum allowable individual dosage which should yield a good therapeutic result without side effects.