Publications by authors named "Antoinette G Am Zehnhoff-Dinnesen"
Genetic heterogeneity makes it difficult to identify the causal genes for hearing loss. Studies from previous decades have mapped numerous genetic loci, providing critical supporting evidence for gene discovery studies. Despite widespread sequencing accessibility, many historically mapped loci remain without a causal gene.
View Article and Find Full Text PDFRecommendations for Age-Appropriate Testing, Timing, and Frequency of Audiologic Monitoring During Childhood Cancer Treatment: An International Society of Paediatric Oncology Supportive Care Consensus Report.
JAMA Oncol
October 2021
Article Synopsis
- Ototoxicity is a significant long-term effect of certain cancer treatments in children, making early detection and monitoring of hearing loss crucial for managing their overall care.
- The Ototoxicity Task Force, consisting of experts from various fields, developed standardized recommendations for monitoring hearing loss during pediatric cancer treatment.
- Key findings indicate that children undergoing ototoxic treatments should have regular hearing assessments, including baseline evaluations and ongoing monitoring throughout therapy, to ensure timely interventions when needed.
Reduced speech-in-noise intelligibility is one of the main difficulties experienced by children with auditory processing disorder (APD). Previous studies have established a relationship between the function of the medial olivocochlear system (MOCS) and reduced inhibition of otoacoustic emissions (OAE) in children with APD. This study measured spontaneous OAE (SOAE) in 27 children with reduced speech-in-noise intelligibility, and those of a control group matched by gender and age.
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