Publications by authors named "Antoinette Frick"
Background: Raltegravir is an HIV integrase strand transfer inhibitor recommended for use in pregnancy. The aim of this study was to assess risk of birth defects and other suboptimal outcomes following prenatal exposure to raltegravir.
Methods: We used pooled, prospectively-collected individual patient data from studies in the European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC).
Introduction: Adolescents living with HIV are subject to multiple co-morbidities, including growth retardation and immunodeficiency. We describe growth and CD4 evolution during adolescence using data from the Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) global project.
Methods: Data were collected between 1994 and 2015 from 11 CIPHER networks worldwide.
Article Synopsis
- Introduction of antiretroviral treatment has significantly reduced mortality rates in HIV patients, but those transitioning from pediatric to adult care, especially adolescents without proper viral control, still face high mortality risks.
- A retrospective study analyzed the deaths of perinatally infected HIV patients transitioning to adult care between 2009 and 2019, revealing that poor treatment adherence and advanced HIV stages contributed to mortality.
- Findings showed a 3.5% mortality rate in the cohort, with many patients experiencing serious comorbidities and complications, underlining the need for improved care strategies for young adults in this population.
Background: There are not enough nationwide studies on perinatal HIV transmission in connection with a combination of antiretroviral treatments in Spain. Our objectives were to study sociodemographic changes and trends in the rates of HIV diagnoses and perinatal transmission in Spain from 1997 to 2015.
Methods: A retrospective study using data from Spanish Paediatric HIV Network (CoRISpe) and Spanish Minimum Basic Data Set (MDBS) was performed.
Background: Staphylococcus aureus is a major cause of bacteremia in children and is associated with high morbidity. Complete data are lacking on the incidence, related risk factors and mortality associated with this infection.
Methods: Descriptive study including patients younger than 16 years admitted to a tertiary reference hospital, with blood cultures exclusively positive for S.