Publications by authors named "Antoine Zoghbi"

Article Synopsis
  • Urinary tract infections (UTIs) are common in emergency departments, and this study evaluated the necessity of broad-spectrum treatment for hospitalized patients with community-acquired UTIs (CAUTIs).
  • Conducted over two years at a major Lebanese tertiary care center, the study analyzed data from adult patients to determine treatment adherence, characteristics of CAUTIs, and risks associated with extended spectrum beta-lactamase (ESBL) infections.
  • Results indicated that most patients received appropriate ESBL-targeting treatment, but 46% required adjustments, emphasizing the need for better monitoring of drug-resistant bacteria and stronger local treatment guidelines.
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On August 4, 2020, Beirut experienced a large explosion when 2750 tons of ammonium nitrate detonated in the Beirut port resulting in more than 220 deaths, 76 000 injuries, 300 000 people displaced, and 15 billion dollars loss in property damage. Hôtel-Dieu de France (HDF), one of the largest university hospitals in the capital, has an emergency department that typically accommodates 25 patients. On that night, it received the largest number of injuries and had to accommodate more than 700 casualties within a few hours of the blast.

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In December 2019, a new emerging virus causing mild-to-severe pneumonia was detected in China. The virus was described as a variant of SARS-CoV and was called SARS-CoV-2, then declared a pandemic by the WHO on 11 March 2020. Millions of people contracted the virus and presented with a symptomatology of variable severity, including upper respiratory tract symptoms, systemic symptoms and diarrhea.

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Introduction: Yellow lupine seeds (Tourmos) are frequently used as snack in Lebanon but their potential toxicity is extremely rare (five published cases) and often undiagnosed.

Case Reports: Two patients presented with anticholinergic syndrome (mydriasis, mouth dryness, palpitations, general malaise) after ingestion of 200-500 g of bitter lupine seeds (not soaked enough in water). No other cause of intoxication was found, and symptoms disappeared spontaneously in 24-36h.

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Background: Antiplatelet therapy with clopidogrel decreases ischemic complication especially in patients with acute coronary syndromes or after percutaneous coronary interventions. Our study was designed to test the effects of clopidogrel on soluble CD40 ligand (sCD40l) and on high-sensitivity C-reactive protein (hs-CRP) in patients with stable coronary artery disease (CAD).

Methods: This is a randomized, double-blind, placebo-controlled study.

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