Massive gastric polyposis associated with a germline SMAD4 gene mutation.

Juvenile polyposis syndrome (JPS) is a rare autosomal dominant disorder characterized by the development of multiple hamartomatous polyps in the gastrointestinal tract. Polyps are most common in the colorectum (98% of patients) and the stomach (14%). Causative mutations for JPS have been identified in two genes to date, SMAD4 and BMPR1A.

[Rectal bleeding during pregnancy].

Background: Ischaemic colitis is a relatively rare disease that predominantly affects elderly patients. This disorder has varying underlying causes and diverse clinical symptoms.

Case Description: A 29-year-old primigravida was admitted to our hospital with rectal bleeding and diffuse abdominal pain.