Publications by authors named "Antoine Deney"
Article Synopsis
- * A 26-year-old male diver experienced DCS after diving at a significant depth, underwent PFO closure, but 10 years later showed symptoms indicating the prosthesis had reopened.
- * The case emphasizes the difficulties in managing PFO in divers and questions the long-term effectiveness of PFO closures, suggesting that diving conditions might affect the durability of such medical implants.
Article Synopsis
- Intensive cardiac care units (ICCU) in France have diversified from monitoring arrhythmias post-heart attack to treating various cardiac conditions, with acute coronary syndromes (ACS) being the most common cause for admission.
- A study of 1499 patients revealed that many have additional health concerns, with a significant portion requiring advanced therapies but a majority not needing invasive procedures.
- Overall, patients tend to have brief hospital stays with a low rate of major adverse events, although acute heart failure (AHF) patients face higher risks and resource use.
Article Synopsis
- The study investigated the prevalence of recreational drug use among patients admitted to intensive cardiac care units (ICCU) and its effect on major adverse events (MAEs) during hospitalization.
- Out of 1499 patients tested, 11% were positive for recreational drugs, with cannabis being the most common, yet only 57% self-reported their use.
- Patients using recreational drugs experienced significantly higher rates of in-hospital MAEs compared to non-users, with drugs like cannabis, cocaine, and MDMA showing independent associations with worse outcomes.
Aims: Coronary artery disease (CAD) is a common cause of heart failure (HF). It remains unclear who, when and why to direct towards coronary revascularization. The outcomes of coronary revascularization in HF patients are still a matter of debate nowadays.
View Article and Find Full Text PDFTransthyretin cardiac amyloidosis (ATTR-CA) is an increasingly recognized disease that often results in heart failure and death. Traditionally, biological staging systems are used to stratify disease severity. Reduced aerobic capacity has recently been described as useful in identifying higher risk of cardiovascular events and death.
View Article and Find Full Text PDFThe rod-shaped adult cardiomyocyte (CM) harbors a unique architecture of its lateral surface with periodic crests, relying on the presence of subsarcolemmal mitochondria (SSM) with unknown role. Here, we investigated the development and functional role of CM crests during the postnatal period. We found in rodents that CM crest maturation occurs late between postnatal day 20 (P20) and P60 through both SSM biogenesis, swelling and crest-crest lateral interactions between adjacent CM, promoting tissue compaction.
View Article and Find Full Text PDFBackground: The evolution of patients hospitalized with coronavirus disease 2019 (COVID-19) is still hard to predict, even after several months of dealing with the pandemic.
Aims: To develop and validate a score to predict outcomes in patients hospitalized with COVID-19.
Methods: All consecutive adults hospitalized for COVID-19 from February to April 2020 were included in a nationwide observational study.
BACKGROUND Heart failure (HF) most commonly occurs due to ischemic heart disease from stenotic coronary artery disease (CAD). HF is classified into 3 groups based on the percentage of the ejection fraction (EF): reduced (HFrEF), mid-range (HFmrEF), and preserved (HFpEF). This retrospective study included 573 patients who presented with HF based on the evaluation of EF and were evaluated for CAD by coronary angiography before undergoing coronary angioplasty at a single center in Toulouse, France.
View Article and Find Full Text PDFArticle Synopsis
- The Critical COVID France (CCF) study examined the effects of COVID-19 on 2868 hospitalized patients, focusing on those aged 18-45, who made up 11.2% of the sample.
- Young patients (18-45 years old) had lower rates of severe outcomes like ICU transfers and in-hospital deaths compared to older patients, but they experienced higher rates of certain cardiovascular issues like pericarditis and myocarditis.
- Despite lower overall severity, COVID-19 still posed significant cardiovascular risks for young patients, highlighting the importance of understanding its impacts on this age group.
Sports participation and myocarditis: Influence of sport types on disease severity.
Int J Cardiol Heart Vasc
December 2021
Objective: To study, in the context of acute myocarditis (AM) in sportsmen, the association between the category of sport practiced and the severity of AM.
Design: Retrospective study.
Setting: Single tertiary center.
Aims: Mechanical complications (MC) (i.e., free wall rupture (FWR), papillary muscle rupture (PMR) and ventricular septal rupture (VSR)) are rare complications of ST- elevation acute myocardial infarction (STEMI).
View Article and Find Full Text PDFBackground: Although women account for up to half of patients hospitalized for coronavirus disease 2019 (COVID-19), no specific data have been reported in this population.
Aims: To assess the burden and impact of cardiovascular comorbidities in women with COVID-19.
Methods: All consecutive patients hospitalized for COVID-19 across 24 hospitals from 26 February to 20 April 2020 were included.
Background: The coronavirus disease 2019 (COVID-19) pandemic has led to a public health crisis. Only limited data are available on the characteristics and outcomes of patients hospitalized for COVID-19 in France.
Aims: To investigate the characteristics, cardiovascular complications and outcomes of patients hospitalized for COVID-19 in France.
Background: Although cardiovascular comorbidities seem to be strongly associated with worse outcomes in patients with coronavirus disease 2019 (COVID-19), data regarding patients with preexisting heart failure are limited.
Aims: To investigate the incidence, characteristics and clinical outcomes of patients with COVID-19 with a history of heart failure with preserved or reduced ejection fraction.
Methods: We performed an observational multicentre study including all patients hospitalized for COVID-19 across 24 centres in France from 26 February to 20 April 2020.
Prognostic value of right ventricular dilatation in patients with COVID-19: a multicentre study.
Eur Heart J Cardiovasc Imaging
March 2022
Aims: Although cardiac involvement has prognostic significance in coronavirus disease 2019 (COVID-19) and is associated with severe forms, few studies have explored the prognostic role of transthoracic echocardiography (TTE). We investigated the link between TTE parameters and prognosis in COVID-19.
Methods And Results: Consecutive patients with COVID-19 admitted to 24 French hospitals were retrospectively included.
Background: Systems of care have been challenged to control progression of the COVID-19 pandemic. Whether this has been associated with delayed reperfusion and worse outcomes in French patients with ST-segment elevation myocardial infarction (STEMI) is unknown.
Aim: To compare the rate of STEMI admissions, treatment delays, and outcomes between the first peak of the COVID-19 pandemic in France and the equivalent period in 2019.
Background: Coronavirus disease 2019 (COVID-19) has been associated with coagulation disorders, in particular high concentrations of D-dimer, and increased frequency of venous thromboembolism.
Aim: To explore the association between D-dimer at admission and in-hospital mortality in patients hospitalised for COVID-19, with or without symptomatic venous thromboembolism.
Methods: From 26 February to 20 April 2020, D-dimer concentration at admission and outcomes (in-hospital mortality and venous thromboembolism) of patients hospitalised for COVID-19 in medical wards were retrospectively analysed in a multicenter study in 24 French hospitals.
Background Coronavirus disease 2019 (COVID-19) is a respiratory disease associated with thrombotic outcomes with coagulation and endothelial disorders. Based on that, several anticoagulation guidelines have been proposed. We aimed to determine whether anticoagulation therapy modifies the risk of developing severe COVID-19.
View Article and Find Full Text PDFBackground: Our study aimed to compare the clinical outcomes of patients with and without diabetes admitted to hospital with COVID-19.
Methods: This retrospective multicentre cohort study comprised 24 tertiary medical centres in France, and included 2851 patients (675 with diabetes) hospitalized for COVID-19 between 26 February and 20 April 2020. A propensity score-matching (PSM) method (1:1 matching including patients' characteristics, medical history, vital statistics and laboratory results) was used to compare patients with and without diabetes (n = 603 per group).
Higher rates of severe COVID-19 have been reported in kidney transplant recipients (KTRs) compared to nontransplant patients. We aimed to determine if poorer outcomes were specifically related to chronic immunosuppression or underlying comorbidities. We used a 1:1 propensity score-matching method to compare survival and severe disease-free survival (defined as death and/or need for intensive care unit [ICU]) incidence in hospitalized KTRs and nontransplant control patients between February 26 and May 22, 2020.
View Article and Find Full Text PDFAims: In amyloid patients, cardiac involvement dramatically worsens functional capacity and prognosis. We sought to study how the cardiopulmonary exercise test (CPET) could help in functional assessment and risk stratification of patients with cardiac amyloidosis (CA).
Methods And Results: We carried out a multicentre study including patients with light chain (AL) or transthyretin (TTR) CA.