Publications by authors named "Antoine Breton"

Objective: To analyse outcomes after adult right ex-situ split graft liver transplantations (RSLT) and compare with available outcome benchmarks from whole liver transplantation (WLT).

Summary Background Data: Ex-situ SLT may be a valuable strategy to tackle the increasing graft shortage. Recently established outcome benchmarks in WLT offer a novel reference to perform a comprehensive analysis of results after ex-situ RSLT.

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Background: Hypothermic oxygenated perfusion (HOPE) improves outcomes of marginal liver grafts. However, to date, no preservation solution exists for both static cold storage (SCS) and HOPE.

Methods: After 30 min of asystolic warm ischemia, porcine livers underwent 6 h of SCS followed by 2 h of HOPE.

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Article Synopsis
  • Researchers wanted to find out how to tell if a redo liver transplant (redo-LT) is successful or not, especially since there aren't many organs available to transplant.
  • They looked at data from 22 hospitals from 2010 to 2018, focusing on certain patients who had a better chance of having a good outcome after the surgery.
  • They found that while most patients had a high survival rate after 1 year, those who had redo-LT for specific complications did not do as well, showing that some cases are riskier than others.
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Article Synopsis
  • The study investigates the use of ex situ hypothermic oxygenated perfusion (HOPE) for preserving split liver grafts, comparing it to traditional static cold storage methods.
  • Results show that all grafts in the HOPE-Split group were successfully transplanted without any graft loss or recipient deaths over a median follow-up of 7.5 months.
  • The HOPE-Split method significantly reduced cold storage time and improved preservation outcomes while maintaining similar safety profiles compared to static methods.
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Prophylactic surgery of familial adenomatous polyposis (FAP) includes total colectomy with ileorectal anastomosis (IRA) to proctocolectomy with ileoanal anastomosis (IAA). Surgical guidelines rely on studies without systematic endoscopic follow-up and treatment. Our aim was to report our experience based on a different approach: therapeutic follow-up, comparing in this setting IRA and IAA in terms of oncological safety and quality of life.

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