Publications by authors named "Antoine Blain"
Long-term Outcome of Risankizumab in Crohn's Disease: a Real-world GETAID Study.
Clin Gastroenterol Hepatol
December 2024
Background & Aims: The aim of this study was to assess the long-term effectiveness and safety of risankizumab maintenance treatment in a large real-world cohort of patients with Crohn's Disease (CD).
Methods: From May 2021 to August 2023, all consecutive patients with CD treated with risankizumab in 25 GETAID centers have been retrospectively included. The primary endpoint was steroid-free clinical remission (Harvey Bradshaw Index [HBI] <5) at 52 weeks.
Article Synopsis
- - This study focuses on the high risks of venous thromboembolism (VTE) and cardiovascular disease (CVD) in patients with ulcerative colitis (UC) and aims to identify prevalence and risk factors in a large patient population.
- - Conducted in 33 referral centers across France and Belgium, the research involved a questionnaire filled out by 1,071 UC patients to gather self-reported data on their VTE and CVD risk factors, aligning with international guidelines.
- - Findings revealed that over one-third of UC patients reported no cardiovascular risk factors (CVRF), and around 91% had no strong VTE risk factors, suggesting that many patients may have lower risks than anticipated and indicating the need
Background: The exact etiology of transient epileptic amnesia (TEA) is currently unknown. In older individuals, common neurodegenerative dementias and small-vessel diseases (SVDs) could be major contributors. We examined these hypotheses on the basis of imaging analysis.
View Article and Find Full Text PDFBackground: Laparoscopic resection (LR) offers significant advantages compared to open resections for gastric gastrointestinal stromal tumours (GISTs). We aimed to evaluate whether LR outcomes jeopardised short and long-term outcomes of patients with large GISTs.
Patients And Methods: Among 50 patients undergoing surgery for gastric GISTs, 12 underwent LR for large GISTs (>5 cm).
Background And Aims: Few studies have been conducted addressing the safety of thiopurine treatment in pregnant women with inflammatory bowel disease (IBD). The aim of this study was to evaluate the pregnancy outcome of women with IBD who have been exposed to thiopurines.
Methods: 215 pregnancies in 204 women were registered and documented in the CESAME cohort between May 2004 and October 2007.
Background: Since the first laparoscopic cholecystectomy was performed in 1987, the surgical applications of laparoscopy have grown to involve most areas of general surgery. Until recently, however, major liver surgery remained outside of the scope of minimally invasive surgery. Building on advances in laparoscopic equipment, techniques, and ongoing experience in hepatic surgery, major liver resection has been performed laparoscopically in some select centers.
View Article and Find Full Text PDFHepatic portal vein gas has been documented in numerous conditions and is traditionally regarded as a poor prognostic sign. There are, however, several reports of portal vein gas with a benign course. We report the first case of transient hepatic portal vein gas secondary to the ingestion of a caustic substance.
View Article and Find Full Text PDFBackground: The Vienna classification of Crohn's disease (CD) distinguishes three patient subgroups according to disease behavior: stricturing, penetrating, and inflammatory. Our aim was to assess the long-term evolution of the disease behavior of CD and to determine the predictive factors and prognostic implications of this evolution.
Methods: Occurrence and predictive factors of a stricturing and/or a penetrating complication were searched for in 2,002 patients with CD studied retrospectively.