Publications by authors named "Antje Schulze"
Article Synopsis
- - A clinical trial compared intensive treatment strategies for non-M3 AML in patients aged 60 and over against a standard treatment known as CSA, involving a total of 1,286 participants.
- - The study found that rates of complete remission at 90 days and five-year event-free survival were similar across CSA and the other intensive treatment groups, with no significant differences observed.
- - Overall, the more intensive treatment strategies did not lead to better outcomes in terms of event-free survival or overall survival compared to the standard CSA treatment based on the evaluated data.
Ann Hematol
September 2021
Article Synopsis
- Relapse of acute leukemia is common and complicated, with only 74.2% of 1621 patients achieving complete remission after initial treatment phases.
- Among non-refractory patients, 48.4% relapsed, primarily within the first 18 months, with the possibility of achieving a second complete remission (CR2) depending on age and other factors.
- The study highlights that while overall survival rates are low, they improve significantly with hematopoietic cell transplantation (HCT) and factors like longer initial remission periods; however, relapse remains a significant challenge in treatment.
