Publications by authors named "Antje S Mefferd"

Purpose: The purpose of this study was twofold: (a) to determine whether there are speech rhythm differences between preschool-age children who stutter that were eventually diagnosed as persisting (CWS-Per) or recovered (CWS-Rec) and children who do not stutter (CWNS), using empirical spectral analysis and empirical mode decomposition of the speech amplitude envelope, and (b) to determine whether speech rhythm characteristics close to onset are predictive of later persistence.

Method: Fifty children (3-4 years of age) participated in the study. Approximately 2-2.

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This study pursued two goals: (1) to establish range of motion (ROM) demand tiers (i.e., low, moderate, high) specific to the jaw (J), lower lip (LL), posterior tongue (PT), and anterior tongue (AT) for multisyllabic words based on the articulatory performance of neurotypical talkers and (2) to identify demand- and disease-specific articulatory performance characteristics in talkers with amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD).

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Although researchers have recognized the need to better account for the heterogeneous perceptual speech characteristics among talkers with the same disease, guidance on how to best establish such dysarthria subgroups is currently lacking. Therefore, we compared subgroup decisions of two data-driven approaches based on a cohort of talkers with Huntington's disease (HD): (1) a statistical clustering approach (STATCLUSTER) based on perceptual speech characteristic profiles and (2) an auditory free classification approach (FREECLASS) based on listeners' similarity judgments. We determined the amount of overlap across the two subgrouping decisions and the perceptual speech characteristics driving the subgrouping decisions of each approach.

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Purpose This study aimed to determine how tongue and jaw displacement changes impact acoustic vowel contrast in talkers with amyotrophic lateral sclerosis (ALS) and controls. Method Ten talkers with ALS and 14 controls participated in this study. Loud, clear, and slow speech cues were used to elicit tongue and jaw kinematic as well as acoustic changes.

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Purpose This study sought to determine the feasibility of using phonetic complexity manipulations as a way to systematically assess articulatory deficits in talkers with progressive dysarthria due to Parkinson's disease (PD). Method Articulatory kinematics were recorded using three-dimensional electromagnetic articulography from 15 talkers with PD (58-84 years old) and 15 healthy controls (55-80 years old) while they produced target words embedded in a carrier phrase. Majority of the talkers with PD exhibited a relatively mild dysarthria.

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Given the crucial role of speech sounds in human language, it may be beneficial for speech to be supported by more efficient auditory and attentional neural processing mechanisms compared to nonspeech sounds. However, previous event-related potential (ERP) studies have found either no differences or slower auditory processing of speech than nonspeech, as well as inconsistent attentional processing. We hypothesized that this may be due to the use of synthetic stimuli in past experiments.

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Objective: Dysarthric speech of persons with Huntington disease (HD) is typically described as hyperkinetic; however, studies suggest that dysarthria can vary and resemble patterns in other neurologic conditions. To test the hypothesis that distinct motor speech subgroups can be identified within a larger cohort of patients with HD, we performed a cluster analysis on speech perceptual characteristics of patient audio recordings.

Methods: Audio recordings of 48 patients with mild to moderate dysarthria due to HD were presented to 6 trained raters.

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Purpose This study sought to identify the articulator-specific mechanisms that underlie reduced and enhanced acoustic vowel contrast in talkers with dysarthria due to Parkinson's disease (PD). Method Seventeen talkers with mild-moderate dysarthria due to PD and 17 controls completed a sentence repetition task using typical, slow, loud, and clear speech. Tongue and jaw articulatory movements were recorded using 3D electromagnetic articulography.

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It is virtually impossible for a speaker to produce identical articulatory movements across several repetitions of the same utterance. This study examined how kinematic endpoint variability, defined as the positional variability of an articulator at its positional extremum, changes in response to cued speech behavioral modifications. As a second step, this study examined the strength of association between articulator speed and kinematic endpoint variability.

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Exercise mode (i.e., resistance training, endurance training) is known to yield mode-specific effects on strength and endurance of muscles that are directly targeted during the exercise.

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Background: Multiple sclerosis can affect the speech motor system and result in dysarthria.

Objectives: This pilot study sought to identify tongue, lip, and jaw motor deficits in persons with dysarthria due to multiple sclerosis (PwDMS) to better understand the speech motor mechanisms that underlie their aberrant speech.

Methods: Tongue and jaw movements during "ai" and lower lip and jaw movements during "bob"were examined in eleven PwDMS and fourteen age- and sex-matched controls using three-dimensional electromagnetic articulography.

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Purpose: This study sought to determine decoupled tongue and jaw displacement changes and their specific contributions to acoustic vowel contrast changes during slow, loud, and clear speech.

Method: Twenty typical talkers repeated "see a kite again" 5 times in 4 speech conditions (typical, slow, loud, clear). Speech kinematics were recorded using 3-dimensional electromagnetic articulography.

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The degree of speech movement pattern consistency can provide information about speech motor control. Although tongue motor control is particularly important because of the tongue's primary contribution to the speech acoustic signal, capturing tongue movements during speech remains difficult and costly. This study sought to determine if formant movements could be used to estimate tongue movement pattern consistency indirectly.

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Purpose: Tongue strength and endurance are important for swallowing and upper airway patency. Physical activity positively affects targeted and non-targeted skeletal muscles; however, little is known about the indirect effect of physical activity on tongue muscles. This study sought to determine if tongue muscle performance differs between highly active and non-active individuals and if such an effect varies with age.

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This study investigated speaking rate effects on articulatory pattern consistency in talkers with mild amyotrophic lateral sclerosis (ALS) to better understand speech rate declines during the early stages of speech deterioration. Eight talkers with mild ALS and 11 controls repeated a sentence at their typical rate, an accelerated rate, and a reduced rate. Lip and jaw movements were captured using a 3-D motion capture system.

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PURPOSE To improve our understanding about the underlying factors of aging-related speaking rate decline, the authors sought to determine if lip and jaw speeds are physiologically constrained in older adults. METHOD Thirty-six females-10 young adults (ages 22-27 years), 9 middle-aged adults (ages 45-55 years), 10 young-old adults (65-74 years), and 7 very old adults (ages 87-95 years)-completed metronome-paced syllable repetitions while moving the lower lip or jaw to a fixed target with each repetition. Metronome paces incrementally increased from 1.

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The sensory and gastrointestinal changes that occur with ageing affect older adults' food and liquid intake. Any decreased liquid intake increases the risk for dehydration. This increased dehydration risk is compounded in older adults with dysphagia.

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Purpose: The goal of this study was to determine if talkers with ALS are limited in their ability to increase lower lip and jaw speed at an early stage of the disease when their speaking rate and intelligibility are only minimally or not affected.

Method: A novel metronome paced fixed-target task was used to assess movement speed capacities during lower lip and jaw oscillations in seven talkers with ALS and seven age and gender matched controls.

Results: Lower lip peak speeds were significantly lower in talkers with mild ALS than in healthy talkers suggesting a lower lip speed constraint in talkers with mild ALS.

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Purpose: Although a growing body of literature has identified the positive effects of visual speech on speech and language learning, oral movements of infant-directed speech (IDS) have rarely been studied. This investigation used 3-dimensional motion capture technology to describe how mothers modify their lip movements when talking to their infants.

Method: Lip movements were recorded from 25 mothers as they spoke to their infants and other adults.

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Purpose: In this investigation, the authors determined the strength of association between tongue kinematic and speech acoustics changes in response to speaking rate and loudness manipulations. Performance changes in the kinematic and acoustic domains were measured using two aspects of speech production presumably affecting speech clarity: phonetic specification and variability.

Method: Tongue movements for the vowels /ia/ were recorded in 10 healthy adults during habitual, fast, slow, and loud speech using three-dimensional electromagnetic articulography.

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