Publications by authors named "Anthony Thay"

Bone microarchitecture has several clinical implications over and above estimating bone strength. Computed tomography (CT) analysis mainly uses high-resolution peripheral quantitative CT and micro-CT, research imaging techniques, most often limited to peripheral skeleton assessment. Ultra-high-resolution (UHR) CT and photon-counting detector CT, two commercially available techniques, provide images that can approach the spatial resolution of the trabeculae, bringing bone microarchitecture analysis into clinical practice and improving depiction of bone vascularization, tumor matrix, and cortical and periosteal bone.

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Purpose: The aim of this study is to evaluate the image quality and diagnostic performance of angiographic images reconstructed from whole-brain CT perfusion (CTP) using temporal averaging compared to CT angiography (CTA) for the detection of vasospasm.

Materials And Methods: 39 CT studies in 28 consecutive patients who underwent brain CTA with CTP for suspected vasospasm between September 2020 and May 2021 were retrospectively evaluated. The image quality of these two vascular imaging techniques was assessed either quantitatively (image noise, vascular enhancement, signal-to-noise (SNR) and contrast-to-noise (CNR) ratios,) and qualitatively (4 criteria assessed on a 5-point scale).

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Article Synopsis
  • The study aimed to compare the image quality of CT angiography at different tube voltages using deep learning-based reconstruction (DLR) versus hybrid iterative reconstruction (H-IR).
  • Retrospective analysis of 102 patients showed that DLR significantly improved image quality and reduced noise at lower radiation doses compared to H-IR, particularly with an 80 kVp setting.
  • Overall, DLR provided superior image quality in terms of both quantitative measures (like arterial attenuation) and qualitative assessments, although it had limitations for arteries near the aortic arch.
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