Efficacy of transdermal ketoprofen for delayed onset muscle soreness.

Objective: To determine the efficacy of transdermal ketoprofen in reducing delayed-onset muscle soreness (DOMS), limiting systemic absorption, and improving postexercise function following repetitive muscle contraction.

Design: Double-blind, placebo-controlled clinical trial.

Setting: OrthoMed, University of California at San Diego, La Jolla, CA, U.