Operation Blood Rain Phase 2: Evaluating the Effect of Airdrop on Fresh and Stored Whole Blood.

Background: Transfusion of whole blood (WB) is a lifesaving treatment that prolongs life until definitive surgical intervention can be performed; however, collecting WB is a time-consuming and resource-intensive process. Furthermore, it may be difficult to collect sufficient WB at the point of injury to treat critically wounded patients or multiple hemorrhaging casualties. This study is a follow-up to the proof-of-concept study on the effect of airdrop on WB.

Etomidate is associated with mortality and adrenal insufficiency in sepsis: a meta-analysis*.

Objective: To evaluate the effects of single-dose etomidate on the adrenal axis and mortality in patients with severe sepsis and septic shock.

Design: A systematic review of randomized controlled trials and observational studies with meta-analysis.

Setting: Literature search of EMBASE, Medline, Cochrane Database, and Evidence-Based Medical Reviews.