Resource use associated with topiramate in migraine prophylaxis.

Purpose: The effect of topiramate prophylaxis on medication use and medical resource use for migraine patients was studied.

Methods: Medical and pharmacy claims from a commercially insured population were analyzed from July 1, 1999, to March 31, 2004. The study sample included patients with at least one physician encounter or facility claim with a diagnosis of migraine at any point during the study's time frame.

Topiramate in migraine prophylaxis: long-term impact on resource utilization and cost.

Objective: To evaluate the medical resource utilization and overall cost of care among patients treated with topiramate (TPM) for migraine prevention in a commercially insured population. Background.-Preventive migraine therapy with TPM significantly reduces the frequency of migraine attacks.

Economic burden of deep-vein thrombosis, pulmonary embolism, and post-thrombotic syndrome.

Purpose: Deep-vein thrombosis (DVT) and pulmonary embolism (PE) are associated with major morbidity and mortality, with their burden often extending to longer-term complications such as event recurrence and post-thrombotic syndrome (PTS). Few data exist on the overall economic burden of DVT and PE and their sequelae. A retrospective observational cohort study was conducted to determine the direct medical costs of a DVT or PE patient across the entire continuum of care.