Publications by authors named "Anthony J Kozielski"
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Synopsis of recent research by authors named "Anthony J Kozielski"
Anthony J Kozielski's research primarily focuses on understanding the mechanisms of chemotherapy resistance and tumor aggressiveness in triple-negative breast cancer (TNBC), particularly the mesenchymal stem-like subtype, through various cellular signaling pathways and molecular interactions.
His studies highlight the role of IL-1A and IL-6 in chemotherapy resistance, as well as the significance of polycomb group protein EZH2 in cancer growth inhibition.
Additionally, he explores the mechanisms underlying cancer cell metastasis, such as the recycling of MT1-MMP by retromer, and evaluates the effectiveness of immunotherapeutic approaches against TNBC in preclinical settings.