Reported impact and protective factors of the care partner role during persistent critical illness: a content analysis.

Background: Patients with persistent critical illness experience prolonged multi-system morbidity, functional impairments, and chronic conditions. As a result, these patients have prolonged intensive care unit admissions. If discharged, they return home with long-term medical dependencies.

The Burden of Disease in Alopecia Areata: Canadian Online Survey of Patients and Caregivers.

Background: Alopecia areata (AA) is associated with negative impacts on the quality of life (QoL). Data on this impact are lacking for Canadian patients and their caregivers.

Objective: This study aims to investigate the burden of AA on Canadian patients and their caregivers.

Biomarkers in alopecia Areata: A systematic review and meta-analysis.

Background: Alopecia areata (AA) is an autoimmune non-scarring alopecia that affects the scalp or any hair-bearing areas in the body. The pathophysiology of AA is complex, but Th1, Th2, and Th17 cytokines dysregulation, as well as chemokines, immunoglobulins and other biomarkers have been shown to play a role in the pathogenesis of the disease.

Objective: To conduct a systematic review and Meta-analysis to identify biomarkers that reflect AA activity and severity that could be used to better assess disease activity and response in both trials and clinical practice.