Publications by authors named "Anthony F Tierno"
Article Synopsis
- - Pyridinium and related -alkyl(heteroaryl)onium salts are important in organic chemistry for creating various compounds, but their synthesis methods have not advanced much recently.
- - This study introduces a new method using bis(cationic nitrogen-ligated I(iii) hypervalent iodine reagents (HVIs) to efficiently produce a wide range of these onium salts from alkenoic acids, marking a novel approach by directly utilizing olefins.
- - The reactions yield high results in mild conditions, allowing for diverse aromatic heterocycles to be incorporated, and demonstrate significant potential for creating different nitrogen heterocycles through subsequent derivatizations.
European J Org Chem
March 2018
Article Synopsis
- * The method produces HFIP-acetals that can easily be modified with various nucleophiles, offering flexibility for further chemical reactions.
- * The approach is shown to be beneficial in modifying natural products, aiding diversity-oriented synthesis, while early experiments suggest the shape of the alcohol significantly influences the reaction outcomes, which could help predict results in complex molecule creation.
Article Synopsis
- High valent metal complexes have become crucial in modern catalysis over the last two decades, particularly for creating carbon-heteroatom bonds.
- The success of this chemistry relies on finding effective oxidants that can support these high oxidation state complexes, providing necessary heteroatom ligands for reactions.
- Hypervalent iodine reagents are highlighted as key tools, offering versatile reactivity under mild conditions while being eco-friendly, non-toxic, and cost-effective compared to traditional oxidants.
