Publications by authors named "Anthony Darby"

Purpose: Chronic obstructive pulmonary disease (COPD) is associated with substantial morbidity, including impaired health-related quality of life (HRQoL). Despite the prominent role of occupational factors in the aetiology of COPD, the relationship between these exposures and HRQoL has not been well elucidated.

Methods: A subpopulation from an epidemiological study, designed to assess the workplace contribution to COPD, was administered the EQ5D HRQoL tool.

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Background: Although occupational exposure is a known risk factor for Chronic Obstructive Pulmonary Disease (COPD), it is difficult to identify specific occupational contributors to COPD at the individual level to guide COPD prevention or for compensation. The aim of this study was to gain an understanding of how different expert clinicians attribute likely causation in COPD.

Methods: Ten COPD experts and nine occupational lung disease experts assigned occupational contribution ratings to fifteen hypothetical cases of COPD with varying combinations of occupational and smoking exposures.

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Article Synopsis
  • - The study aimed to evaluate how workplace exposures contribute to the risk of chronic obstructive pulmonary disease (COPD) in a community with many industrial jobs in Sheffield, U.K.
  • - Researchers collected data from 4,000 residents over 55 and found that exposure to vapours, gases, dusts, and fumes (VGDF) significantly increased the risk of COPD, with notable population attributable risk values indicating a strong association.
  • - This study supports existing evidence linking occupational factors to COPD, demonstrating that both self-reported exposure and a job exposure matrix (JEM) method highlight risks in an industrial community.
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Chronic Obstructive Pulmonary Disease (COPD) is a progressive respiratory disease associated with increasing morbidity and mortality worldwide. Whilst tobacco smoking is the important cause, other causes are recognized. This article discusses the contribution that harmful inhaled occupational exposures make to the overall burden of COPD, and goes on to discuss other aspects of the COPD workplace interface.

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