Non-invasive ventilation use in status asthmaticus: 16 years of experience in a tertiary intensive care.

Objective: To describe the use of non-invasive ventilation (NIV) in adults presenting with status asthmaticus to Middlemore Hospital Critical Care Complex (CCC, South Auckland, New Zealand) from 2000 to 2015.

Method: Retrospective review of all adult asthma admissions to the Hospital CCC between 2000 and 2015. Demographic, physiological, treatment data and blood gas results were recorded.

Mortality rate comparison after switching from continuous to prolonged intermittent renal replacement for acute kidney injury in three intensive care units from different countries.

Background: Prolonged intermittent renal replacement therapy (PIRRT) is a dialysis modality for critically ill patients that in theory combines the superior detoxification and haemodynamic stability of the continuous renal replacement therapy (CRRT) with the operational convenience, reduced haemorrhagic risk and low cost of conventional intermittent haemodialysis. However, the extent to which PIRRT should replace these other modalities is uncertain because comparative studies of mortality are lacking. We retrospectively examined the mortality data from three general intensive care units (ICUs) in different countries that have switched their predominant therapeutic approach from CRRT to PIRRT.

Illness severity scoring for Intensive Care at Middlemore Hospital, New Zealand: past and future.

Aim: The Acute Physiological and Chronic Health Evaluation (APACHE) II score is a popular illness severity scoring system for intensive care units. Scoring systems such as the APACHE II allow researchers and clinicians to quantify patient illness severity with a greater degree of accuracy and precision, which is critical when evaluating practice patterns and outcomes, both within or between intensive care units. The study aims to: assess changes in APACHE II scores and hospital-standardised mortality ratio at our ICU over a nine year period from 1 January 1997 to 31 December 2005; assess for changes in the performance of the APACHE II scoring system in predicting patient hospital mortality over the same period; and assess for any clinical subgroups in which APACHE II scoring was particularly inaccurate or imprecise.

Sustained low-efficiency daily diafiltration (SLEDD-f) for critically ill patients requiring renal replacement therapy: towards an adequate therapy.

Background: Sustained low-efficiency daily dialysis (SLEDD) is an increasingly popular renal replacement therapy for intensive care unit (ICU) patients. SLEDD has been previously reported to provide good solute control and haemodynamic stability. However, continuous renal replacement therapy (CRRT) is considered superior by many ICU practitioners, due first to the large amounts of convective clearance achieved and second to the ability to deliver treatment independently of nephrology services.