Subchronic exposure to ; its neurotoxic potentials in young adult female Wistar rats.

Background: (camphor) {CHO} is a chemical substance used mostly amongst the Yoruba ethnic group in Western Nigeria to treat infantile colic during early childhood. This study assess the neurotoxic potentials of following sub-chronic exposure in female albino Wistar rats.

Methods: Twenty-eight female rats (mean weight of 130 g) were randomly selected and assigned into four (4) groups.

Safety effect of fractions from methanolic leaf extract of on reproduction in male wistar rats.

This study evaluates the reproductive toxicity of ethyl acetate and butanolic fractions from crude methanolic leaf extract of in male Wistar rats. Acute toxicity was assessed to determine the safety dose, Sub-chronic reproductive toxicity studies were carried out by administering daily 25, 100 and 400 mg/kg body weight doses of the fractions to respective group of animals and 1 ml of normal saline daily for the control group for 28 days. Blood, epididymis and testes were harvested for reproductive hormones, sperm parameters, and histopathologic analysis respectively.