Publications by authors named "Anthi Stefatos"

Background: Generalized anxiety disorder (GAD) is a debilitating mental health disorder with first-line treatments include cognitive behavioral therapy (CBT) and pharmacotherapy. CBT is costly, time-consuming, and inaccessible. Electronic delivery (e-CBT) is a promising solution to address these barriers.

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Article Synopsis
  • The study explores the effectiveness of an electronically delivered cognitive behavioral therapy (e-CBT) compared to traditional in-person therapy for individuals with major depressive disorder (MDD) during the COVID-19 pandemic.
  • Both treatment methods resulted in significant improvements in depressive symptoms and quality of life, with e-CBT showing higher participant compliance rates.
  • The research suggests that e-CBT with therapist support is a viable alternative for treating MDD, warranting further investigation in future studies.
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Article Synopsis
  • - Major depressive disorder (MDD) is a common and severe mental health issue, with cognitive behavioral therapy (CBT) being the preferred treatment; however, access to traditional in-person CBT can be limited due to various barriers like stigma, cost, and wait times.
  • - This study explores the effectiveness and practicality of an online version of CBT (e-CBT) compared to traditional in-person CBT, hypothesizing that e-CBT will produce similar improvements in depressive symptoms and quality of life.
  • - Participants, aged 18-65, will engage in 12 weeks of e-CBT via a secure digital platform, completing modules and receiving personalized feedback, while their progress will be measured through validated questionnaires and focus groups will assess broader
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Background: Generalized anxiety disorder (GAD) is an extremely prevalent and debilitating mental health disorder. Currently, the gold standard treatment for GAD is cognitive behavioral therapy (CBT) and/or pharmacotherapy. The most common medications used to treat GAD are selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors.

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Numbers are ubiquitous to modern existence and have evolved with humanity over millenia. They structure, record and quantify human behaviour, spiritual belief systems and the evolution of innovation across all spheres of life. Furthermore, cultural identities and interpersonal expression often have numerical components to them for instance rites of passage, population demography and fiscal measures.

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Aripiprazole is a widely clinically employed antipsychotic drug for a range of indications. It has unusual pharmacodynamics as a dopamine D receptor partial-agonist with complex interactions with serotonin receptors and, a relatively unusual long elimination half-life. Although other atypical antipsychotics have been associated with an increased risk of atrial fibrillation, aripiprazole is considered to be relatively neutral in regard to its cardiac risk.

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Aim: Statins have been associated with decreased cognition due to the effects of low concentrations of low-density lipoprotein (LDL) on brain function. This has remained controversial and is particularly relevant to patients with coronary artery disease (CAD), who have an increased risk of cognitive decline and are frequently prescribed statins. This study hypothesized that low concentration of LDL is associated with poor cognition in CAD patients using statins.

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