Publications by authors named "Antal Simay"
Curr Med Chem
January 2004
Article Synopsis
- Cardiac arrhythmias are a key focus in heart-related research, with many antiarrhythmic drugs available, yet clinical trials show serious side effects limit their effectiveness, particularly in reducing arrhythmia-related deaths.
- Amiodarone is known for its strong antiarrhythmic effects but has harmful side effects due to its chemical structure, prompting the need for safer alternatives.
- The study reports the creation of new antiarrhythmic compounds that combine Class I/B and Class III features, discovering GYKI-16638 as a promising candidate with effective antiarrhythmic properties and a better safety profile.
