Publications by authors named "Anshika Kumari"
J Biochem Mol Toxicol
December 2024
Article Synopsis
- - Developing safe medications for neurodegenerative disorders like Alzheimer's (AD) and Parkinson's (PD) is a major challenge, with issues like oxidative stress, mitochondrial dysfunction, and neuroinflammation being prevalent in these diseases.
- - SIRT-1, an important protein that helps regulate oxidative stress and mitochondrial activity, is found to be decreased in models of AD and PD, suggesting its crucial role in maintaining cellular health.
- - Targeting the SIRT-1/PGC-1α pathway could offer new therapeutic strategies for AD and PD by promoting mitochondrial health, cognitive function, and providing protective effects against oxidative damage and inflammation.
