Peroxynitrous Acid Generated In Situ from Acidified HO and NaNO. A Suitable Novel Antimicrobial Agent?

Peroxynitrite (ONOO) and peroxynitrous acid (ONOOH) are known as short acting reactive species with nitrating and oxidative properties, which are associated with their antimicrobial effect. However, to the best of our knowledge, ONOOH/ONOO are not yet used as antimicrobial actives in practical applications. The aim is to elucidate if ONOOH generated in situ from acidified hydrogen peroxide (HO) and sodium nitrite (NaNO) may serve as an antimicrobial active in disinfectants.

Non-touching plasma-liquid interaction - where is aqueous nitric oxide generated?

Nitric oxide is a relatively stable free radical and an important signal molecule in plants, animals, and humans with high relevance for biological processes involving inflammatory processes, e.g. wound healing or cancer.