Publications by authors named "Anselmino M"

Brugada syndrome (BrS) is a genetic condition that increases the risk of life-threatening arrhythmias, which can result in sudden cardiac death (SCD). Implantable loop recorders (ILRs) have become a key tool in managing patients with unexplained syncope, and guidelines advise their use in individuals with recurrent, unexplained syncope or palpitations. However, the role of ILRs in inherited arrhythmic conditions like BrS remains a topic of debate.

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This systematic review aims to evaluate the current evidence regarding safety and efficacy of magnetic sphincter augmentation (MSA) for the treatment of gastroesophageal reflux disease (GERD) after laparoscopic sleeve gastrectomy (LSG). Conversion to Roux-en-Y gastric bypass (RYGB) carries the risk of surgical and metabolic complications and may be contraindicated in patients with normalized or near-normalized body mass index. The LINX™ procedure aims to restore LES competency and to repair the crura.

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Atrial high-rate episodes (AHREs) and subclinical atrial fibrillation (AF) are frequently registered in asymptomatic patients with cardiac implantable electronic devices (CIEDs) and insertable cardiac monitors (ICMs). While an increased risk of thromboembolic events (e.g.

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Article Synopsis
  • Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), specifically semaglutide, show cardiovascular benefits and may reduce the incidence of atrial fibrillation (AF) in high-risk patients.
  • A meta-analysis of 10 randomized clinical trials involving 12,651 patients revealed a 42% reduction in the risk of AF with semaglutide compared to placebo during an average follow-up of 68 months.
  • The study found no significant differences in AF risk reduction based on the route of administration (oral or subcutaneous), as well as no influence from baseline characteristics like diabetes status or BMI.
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Background: The combination of highly localized impedance (LI) and contact force (CF) may improve tissue characterization and lesion prediction during radiofrequency (RF) pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF).

Objective: We report the outcomes of our acute and long-term clinical evaluation of CF-LI-guided PVI in consecutive AF ablation cases from an international multicenter clinical setting.

Methods: Three hundred twenty-four consecutive patients from 20 European centers undergoing RF catheter ablation with the Stablepoint™ catheter were enrolled in the CHARISMA registry.

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Introduction: Revisional bariatric surgery (RBS) for insufficient weight loss/weight regain or metabolic relapse is increasing worldwide. There is currently no large multinational, prospective data on 30-day morbidity and mortality of RBS. In this study, we aimed to evaluate the 30-day morbidity and mortality of RBS at participating centres.

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Background: Cardiac resynchronization therapy (CRT) represents an effective heart failure treatment, associated with reduction in mortality and heart failure hospitalizations. This Italian survey aimed to address relevant CRT issues.

Methods: An online survey was administered to AIAC members.

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  • Atrial fibrillation (AF) is linked to an increased risk of vascular dementia and cognitive impairment due to changes in deep cerebral blood flow, with lenticulostriate arteries (LSAs) being particularly affected.
  • The study used computational fluid dynamics (CFD) and high-resolution MRI to analyze the LSA's shape and its influence on blood flow during AF, identifying key features like MCA size and bifurcation angles.
  • Findings suggest that LSAs with larger angles and smaller MCA sizes may be more susceptible to vascular damage caused by AF, highlighting the importance of LSA morphology in cerebral hemodynamics.
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  • Catheter ablation for atrial fibrillation (AF) is the most common procedure in electrophysiology, aiming to isolate pulmonary veins, but there is insufficient data on severe complications worldwide.
  • A study involved collecting and analyzing data from 23 centers with 33,879 procedures to determine the incidence and management of severe complications during AF ablation.
  • The study found that while severe complications like tamponade and stroke have a low incidence, factors like age, gender, and procedure duration play a role in their occurrence; most patients with complications were discharged after about 5 days.
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Background: Pulsed field ablation (PFA) and very high-power short-duration (vHPSD) radiofrequency ablation are the most recently introduced technologies for atrial fibrillation (AF) ablation. The procedural performance, safety, and effectiveness of PFA vs vHPSD are currently unknown.

Objective: The study aimed to compare PFA with vHPSD for the treatment of paroxysmal or persistent AF.

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The relationship between epicardial adipose tissue (EAT) and atrial fibrillation (AF) has gained interest in recent years. The previous literature on the topic presents great heterogeneity, focusing especially on computed tomography imaging. The aim of the present study is to determine whether an increased volume of left atrial (LA) EAT evaluated at routine pre-procedural cardiac magnetic resonance imaging (MRI) relates to AF recurrences after catheter ablation.

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Background: bariatric surgery stands as an effective intervention for weight loss and improved metabolic control in obesity, although over time there is a proportion of weight regain and type-2-diabetes (T2D) relapse.

Aims: to explore the role of physical activity (PA) after surgery and its impact on metabolic parameters during a 5-year follow-up.

Methods: 148 individuals who underwent bariatric surgery completed scheduled examinations over 5-years.

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  • * This study aimed to analyze how long R-R intervals during AF affect cerebral blood flow and oxygenation using near-infrared spectroscopy (NIRS) in patients undergoing electrical cardioversion.
  • * Findings showed that long R-R intervals significantly lowered diastolic blood pressure and cerebral blood volume, with subsequent decreases in oxygen levels; these changes were temporary and smoothed out over time, suggesting the brain's regulatory mechanisms are at work in response to these blood flow fluctuations.
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  • The study investigates the effectiveness and safety of continuous percutaneous stellate ganglion block (C-PSGB) compared to thoracic epidural anesthesia (TEA) for treating refractory ventricular arrhythmias in patients with advanced heart disease.
  • C-PSGB was performed on 26 patients, resulting in 59% experiencing complete suppression of arrhythmias and 94% showing overall clinical benefits, while TEA had higher side-effect-related discontinuation rates.
  • Overall, the findings suggest that C-PSGB is a promising and safer alternative for managing these heart conditions, especially for patients on anticoagulation therapy.
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Background: Diagnosis of pericarditis may be challenging because not all patients meet the conventional criteria. An overlooked diagnosis implies a longer course of symptoms and an increased risk of recurrences. C-reactive protein (CRP), widely used as an inflammation marker, has some limitations.

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Background: Artificial intelligence (AI) has shown promise in the early detection of various cardiac conditions from a standard 12-lead electrocardiogram (ECG). However, the ability of AI to identify abnormalities from single-lead recordings across a range of pathological conditions remains to be systematically investigated. This study aims to assess the performance of a convolutional neural network (CNN) using a single-lead (D1) rather than a standard 12-lead setup for accurate identification of ECG abnormalities.

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  • Recognizing the cause of cerebral ischemic events is crucial for effective treatment and prevention, yet there are no standard MRI criteria to identify an embolic etiology.
  • This study aims to analyze the MRI characteristics of ischemic brain lesions that occur after transcatheter ablation of atrial fibrillation (AF) by systematically reviewing various studies.
  • Results show that 17.2% of patients developed ischemic lesions post-ablation, primarily small cortical lesions under 10 mm, mostly found in the middle cerebral artery region, with a very low rate of symptomatic issues.
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  • * The study included 23 relevant research articles and compared two key types of AHRE measurements: longest single episodes and cumulative burden over time.
  • * Findings suggest that while a specific duration of AHREs does indicate some thromboembolic risk, even the presence of AHREs—regardless of time—should be factored into assessing individual patient risk for thromboembolic events.
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Current guidelines recommend the use of cardiac magnetic resonance imaging (MRI) for the management of atrial fibrillation (AF). However, the widespread use of cardiac MRI in clinical practice is difficult to achieve. The aim of the present study is to assess whether cardiac MRI can be adopted to identify ablation-induced fibrosis, and its relationship with AF recurrences.

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Background: Highly localized impedance (LI) measurements during atrial fibrillation (AF) ablation have the potential to act as a reliable predictor of the durability of the lesions created.

Objective: We aimed to collect data on the procedural parameters affecting LI-guided ablation in a large multicenter registry.

Methods: A total of 212 consecutive patients enrolled in the CHARISMA registry and undergoing their first pulmonary vein (PV) isolation for paroxysmal and persistent AF were included.

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