Publications by authors named "Anselm Arthur Derda"
Background: MicroRNAs (miRNAs) can regulate gene expression, controlling numerous cellular processes. Dysregulation of miRNA function is linked to various diseases, making them attractive diagnostic and therapeutic targets. Examples include hsa-miR-92a-3p, hsa-miR-126-3p, hsa-miR-143-3p, hsa-miR-145-5p and hsa-miR-204-5p, which are associated with endothelial function.
View Article and Find Full Text PDFObjectives: Cardiovascular comorbidities are common in patients with autoimmune diseases. This study investigates the extent of subclinical atherosclerosis in patients with primary Sjögren's syndrome (pSS). Correlations with clinical factors such as organ involvement (OI) or disease activity were analysed and oxLDL antibodies (oxLDL ab) were measured as potential biomarkers of vascular damage.
View Article and Find Full Text PDFArticle Synopsis
- - Hypertrophic cardiomyopathy (HCM) is a common genetic heart disease that can lead to sudden cardiac death and has two forms: non-obstructive (HNCM) and obstructive (HOCM), which require tailored treatments.
- - This study explored the potential of certain circular RNAs (circRNAs) as biomarkers for HCM by comparing levels in 64 HCM patients and 53 healthy controls, finding significant downregulation of specific circRNAs in patients with HCM.
- - The identified circRNAs (DNAJC6, TMEM56, and MBOAT2) were effective in differentiating HCM patients from healthy controls and showed strong correlations with disease severity in HOCM, highlighting