Acute mesenteric haematoma and hematoperitoneum following a coughing episode induced by COVID-19.

Acute mesenteric haematoma (AMH) is a rare condition and established causes include blunt trauma, aneurysmal rupture, acute pancreatitis and anticoagulant use. A male patient in his 50s presented with abdominal pain and loss of consciousness that was immediately preceded by a prolonged coughing episode. A computed tomography (CT) abdomen-pelvis revealed two acute mesenteric haematomas and haematoperitoneum and admission swabs diagnosed coronavirus disease 2019 (COVID-19).

The role of ERCP in management of retained bile duct stones after laparoscopic cholecystectomy.

Background: Retained bile duct stones after cholecystectomy are an established entity. To find out the incidence of retained common bile duct (CBD) stones after laparoscopic cholecystectomy (LC) in our hospital, we conducted a retrospective study of patients who presented with symptomatic retained stones in the biliary system after a LC.

Methods: Between the period 1992-2000, 824 LCs were performed in our hospital.

Euglycemic hyperinsulinemia augments the cytokine and endocrine responses to endotoxin in humans.

Type 2 diabetes is associated with biochemical evidence of low-grade inflammation, and experimental studies have suggested that both insulin and glucose affect inflammatory responses. To determine the effect of in vivo changes in glucose availability and plasma insulin concentrations in humans, we administered 20 U/kg Escherichia coli lipopolysaccharide (LPS) or saline (control) to 14 subjects during a euglycemic hyperinsulinemic clamp (n = 6) or an infusion of sterile saline (n = 8). Parallel in vitro studies on human whole blood were undertaken to determine whether there was a direct effect of glucose, insulin, and leptin on proinflammatory cytokine production.