Publications by authors named "Anri Baba"
A consistent and uninterrupted supply of pharmaceuticals is essential for optimal pharmacotherapy. However, some cases of supply disruptions and recalls have been reported. In particular, the withdrawal of some drugs from the market was occurred in recent year.
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- The study examines how reactive oxygen species contribute to cell injury from cisplatin, a chemotherapy drug, specifically in renal tubular cells during transient exposure, while also noting that apoptosis occurs during prolonged exposure.
- Researchers found that cyclic AMP has a protective effect against cisplatin-induced necrosis in both cell cultures and rat models, particularly noting the role of protein kinase A in this protective mechanism.
- Elevated levels of TNF-alpha and lipid peroxidation were linked to cisplatin-induced injury, but this damage was mitigated by using p38 MAPK inhibitors and antioxidants, indicating a potential pathway for protecting kidney cells during chemotherapy treatment.