Publications by authors named "Anousheh Paracha"

Timely closure of patient encounters and addressing tasks in the Electronic Health Record (EHR) inbox are essential for quality care and efficiency. Delinquent items in the EHR inbox impact patient care, cost of care, and overall patient and provider experience. This project aimed to improve the management of these items using a quality improvement initiative with a bundled intervention.

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Background: The role of corticosteroids in the treatment of community-acquired pneumonia (CAP) remains uncertain. We conducted an updated meta-analysis to investigate the effectiveness and potential effect modifiers of adjunctive corticosteroids in patients with CAP.

Methods: The protocol of this meta-analysis was registered with PROSPERO (CRD42022354920).

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Preload reserve represents an important concept in the normal physiologic responses of the body to meet the changing metabolic demands. The recruitment of preload in healthy patients leads to an increase in effective circulating blood volume with a concomitant increase in cardiac output. However, in the setting of heart failure (HF), preload augmentation may precipitate HF decompensation.

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Article Synopsis
  • Doctors looked at studies to see if new blood thinners called DOACs are safe and work well for cancer patients who have blood clots.
  • They found that DOACs reduce the chances of blood clots coming back compared to other treatments, like LMWH and VKAs.
  • While DOACs may have a bit of a bleeding risk, they are considered safer and better for most patients who have cancer-related blood clots.
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Preload augmentation represents a critical mechanism for the cardiovascular system to increase effective circulating blood volume to increase cardiac filling pressures and, subsequently, for the heart to increase cardiac output. The splanchnic vascular compartment is the primary source of vascular capacity and thus the primary target for preload recruitment in humans. Under normal conditions, sympathetic stimulation of these primary venous vessels promotes the shift of blood from the splanchnic to the thoracic compartment and elevates preload and cardiac output.

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  • Heart failure prevalence is rising, affecting about 23 million people worldwide, prompting interest in Sodium-Glucose Cotransporter-2 inhibitors (SGLT2i) for treatment in both diabetic and non-diabetic patients.
  • A review of 864 studies found three randomized controlled trials (RCTs) with nearly 10,000 heart failure patients, demonstrating a significant reduction in adverse outcomes when using SGLT2i.
  • The findings support the safe combination of SGLT2i with ARNI therapy to enhance treatment outcomes for specific heart failure patients.
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