RNA-seq SSRs and small RNA-seq SSRs: new approaches in cancer biomarker discovery.

The recent exponential increase in the number of next generation sequencing studies provides a new source of data for the discovery of functional genomics based markers. The RNA-seq and small RNA-seq provide a new source for the discovery of differentially expressed SSRs (simple sequence repeats) as biomarkers in various diseases. In the present study, for the first time, we applied RNA-seq SSR to find new biomarkers for pancreatic cancer (PC) diagnosis.