Publications by authors named "Anoumou Yaotse Dagnra"
Background: Bacterial infections are considered a major cause of morbidity and mortality in patients, especially children, with sickle cell disease.
Objectives: This study aims at determining, a year after the introduction of the 13-valent pneumococcal conjugate vaccine the distribution of severe acute bacterial infections and germs in children with sickle cell disease.
Patients And Methods: Records of children 0 to 15 years of age and admitted from January 1, 2015 to December 31, 2019 (5 y), were examined retrospectively in the four sickle cell monitoring units in Lomé.
Half of rifampicin-resistant Mycobacterium tuberculosis complex isolated from tuberculosis patients in Sub-Saharan Africa have concomitant resistance to pyrazinamide.
PLoS One
November 2017
Background: Besides inclusion in 1st line regimens against tuberculosis (TB), pyrazinamide (PZA) is used in 2nd line anti-TB regimens, including in the short regimen for multidrug-resistant TB (MDR-TB) patients. Guidelines and expert opinions are contradictory about inclusion of PZA in case of resistance. Moreover, drug susceptibility testing (DST) for PZA is not often applied in routine testing, and the prevalence of resistance is unknown in several regions, including in most African countries.
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- Staphylococcus aureus is found in the noses of about 30% of healthy people and can cause skin infections and more severe issues like osteomyelitis and endocarditis.
- New toxic-related conditions have been identified, including toxic shock syndrome and necrotizing pneumonia, the latter being particularly deadly in children, with a 75% fatality rate.
- There is an increase in antibiotic resistance, particularly for vancomycin in hospital settings and methicillin in community settings.