Publications by authors named "Anouf Nematallah"
Importance: Clostridium difficile infection (CDI) is a major burden in health care and community settings. CDI recurrence is of particular concern because of limited treatment options and associated clinical and infection control issues. Fecal microbiota transplantation (FMT) is a promising, but not readily available, intervention.
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- Six compounds were isolated from the aerial parts of the Argentinean plant Hymenoxys robusta, using advanced spectroscopic techniques to determine their structures.
- The isolated compounds include two inositol derivatives and four 3,4-seco-pseudoguaianolides, one of which is called vermeerin.
- Vermeerin demonstrated antimicrobial activity specifically against Staphylococcus aureus and was non-toxic to human-derived macrophages in bioactivity assays.
Background: Streptococcus pneumoniae is a common cause of sporadic invasive infections, but outbreaks of invasive pneumococcal disease are infrequent. In August 2006, a sudden increase in the number of patients presenting with invasive pneumococcal disease was noted at St. Paul's Hospital (Vancouver, Canada).
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