Conjugation of imipenem to silver nanoparticles for enhancement of its antibacterial activity against multi-drugresistant isolates of .

Due to the broad-spectrum of antibiotic resistance, herein we investigated the possibility of using imipenemconjugated silver nanoparticles (IMP-AgNPs) against multidrug-resistant isolates of . For this purpose, 200 clinical isolates were tested against different antibiotics to determine the antimicrobial susceptibility. To identify and resistance genes, PCR was used.