Comparison of conventional scoring systems versus MAGIC score to predict short-term mortality in patients hospitalized for alcoholic hepatitis.

Background: Multiple prognostic models are available to predict mortality in alcoholic hepatitis (AH) which are of modest benefit, but the best model remains unexplored.

Methods: This is a retrospective analysis (2012-2015) of AH patients. Conventional prognostic scoring systems viz.

Spatial correlations of hydrodynamic fluctuations in simple fluids under shear flow: A mesoscale simulation study.

Hydrodynamic fluctuations in simple fluids under shear flow are demonstrated to be spatially correlated, in contrast to the fluctuations at equilibrium, using mesoscopic hydrodynamic simulations. The simulation results for the equal-time hydrodynamic correlations in a multiparticle collision dynamics (MPC) fluid in shear flow are compared with the explicit expressions obtained from fluctuating hydrodynamics calculations. For large wave vectors k, the nonequilibrium contributions to transverse and longitudinal velocity correlations decay as k^{-4} for wave vectors along the flow direction and as k^{-2} for the off-flow directions.

Time correlation functions in the Lebwohl-Lasher model of liquid crystals.

Time correlation functions in the Lebwohl-Lasher model of nematic liquid crystals are studied using theory and molecular dynamics simulations. In particular, the autocorrelation functions of angular momentum and nematic director fluctuations are calculated in the long-wavelength limit. The constitutive relations for the hydrodynamic currents are derived using a standard procedure based on non-negativity of the entropy production.

Hydrodynamic correlations in shear flow: Multiparticle-collision-dynamics simulation study.

The nonequilibrium hydrodynamic correlations of a multiparticle-collision-dynamics (MPC) fluid in shear flow are studied by analytical calculations and simulations. The Navier-Stokes equations for a MPC fluid are linearized about the shear flow and the hydrodynamic modes are evaluated as an expansion in the wave vector. The shear-rate dependence and anisotropy of the transverse and longitudinal velocity correlations are analyzed.

Thermostat for nonequilibrium multiparticle-collision-dynamics simulations.

Multiparticle collision dynamics (MPC), a particle-based mesoscale simulation technique for complex fluid, is widely employed in nonequilibrium simulations of soft matter systems. To maintain a defined thermodynamic state, thermalization of the fluid is often required for certain MPC variants. We investigate the influence of three thermostats on the nonequilibrium properties of a MPC fluid under shear or in Poiseuille flow.

Force fluctuations in stretching a tethered polymer.

The recently proposed fluctuation relation in unfolding forces [Phys. Rev. E 84, 060101(R) (2011)] is reexamined taking into account the explicit time dependence of the force distribution.

Aggregation of rod-like polyelectrolyte chains in the presence of monovalent counterions.

Using molecular dynamics simulations, it is demonstrated that monovalent counterions can induce aggregation of similarly charged rod-like polyelectrolyte chains. The critical value of the linear charge density for aggregation is shown to be close to the critical value for the extended-collapsed transition of a single flexible polyelectrolyte chain, and decreases with increasing valency of the counterions. The potential of mean force along the center of mass reaction coordinate between two similarly charged rod-like polyelectrolytes is shown to develop an attractive well for large linear charge densities.

Ensemble equivalence for counterion condensation on a two-dimensional charged disk.

We study the counterion condensation on a two-dimensional charged disk in the limit of infinite dilution, and compare the energy-temperature relation obtained from the canonical free energy and microcanonical entropy. The microcanonical entropy is piecewise linear in energy, and is shown to be concave for all energies. As a result, even though the interactions are long-ranged, the energy-temperature relation and hence the counterion condensation transition points are identical in both the ensembles.

Phase transitions of a single polyelectrolyte in a poor solvent with explicit counterions.

Conformational properties of a single flexible polyelectrolyte chain in a poor solvent are studied using constant temperature molecular dynamics simulation. The effects of counterions are explicitly taken in to account. Structural properties of various phases and the transition between these phases are studied by tracking the values of asphericity, radius of gyration, fraction of condensed counterions, number of non-bonded neighbours, and Coulomb interaction energies.