Publications by authors named "Anoop Koratala"

Article Synopsis
  • Recent advancements in bronchoscopic techniques have led to a need for comparative data on methods for sampling peripheral pulmonary lesions (PPLs), particularly between bronchoscopy and CT-guided biopsies.
  • A meta-analysis of 363 studies revealed that CT-guided transthoracic biopsy (CT-TBNA) had the highest diagnostic yield (88.9%), followed closely by robot-assisted bronchoscopy (RAB) at 84.8%, while radial endobronchial ultrasound (rEBUS) had the lowest yield at 72%.
  • Despite CT-TBNA being the most effective method, it also had the highest complication rate, prompting a recommendation for more prospective studies to directly compare CT-TBNA and RAB
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Background And Objective: Robotic-assisted bronchoscopy (RAB) has emerged as an advanced technology for lung cancer diagnosis. This review explores the three approved robotic bronchoscopy systems: Ion™ Endoluminal (Intuitive Surgical, Sunnyvale, CA, USA), Monarch™ (Johnson & Johnson, Redwood City, CA, USA), and Galaxy System™ (Noah Medical, San Carlos, CA, USA), and their different operational systems. This narrative review aims to summarize their findings and outcomes for sampling peripheral pulmonary lesions (PPL) suspected of lung cancer.

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Article Synopsis
  • The study investigates the effectiveness of CT-guided core needle biopsies (CNB) in diagnosing ground-glass nodules (GGNs) and subsolid nodules (SSNs) with solid components that are 6 mm or smaller, as these could indicate malignancy.
  • Out of 22 patients assessed, over half were found to have malignant nodules, resulting in a diagnostic accuracy of 86.36% and sensitivity of 85.7% for detecting cancer.
  • The findings suggest that CT-guided CNB is a reliable procedure for evaluating small GGNs and SSNs, offering valuable insight for proper diagnosis and treatment.
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Introduction: Lung cancer remains the leading cause of cancer death worldwide. Subsolid nodules (SSN), including ground-glass nodules (GGNs) and part-solid nodules (PSNs), are slow-growing but have a higher risk for malignancy. Therefore, timely diagnosis is imperative.

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Article Synopsis
  • Ground-glass pulmonary nodules (GGNs) are typically biopsied using a method called percutaneous transthoracic biopsy, but this study focuses on the diagnostic yield of a newer approach using shape-sensing robotic-assisted bronchoscopy (ssRAB).
  • In a retrospective analysis of 22 patients who underwent ssRAB from September 2021 to April 2023, the study found a high overall diagnostic yield of 87% for GGNs, with a sensitivity for malignancy of 88.9%.
  • The results indicated that ssRAB is effective for diagnosing GGNs, including those with minimal solid components, and it has a low risk of procedure-related complications, with adenocarcinoma being the most frequently
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Lung cancer is the deadliest cancer worldwide, therefore, early and prompt diagnosis is essential for better patient outcomes. It is known to have a high predilection for metastasis to the adrenal glands; however, two-thirds of adrenal masses in patients with lung cancer will turn out to be benign, so timely detection is crucial. We present a case of a lung squamous cell carcinoma diagnosed by shape-sensing robotic-assisted bronchoscopy (ssRAB), negative mediastinal and hilar staging with endobronchial ultrasound (EBUS) and transbronchial needle aspiration (TBNA), and a pheochromocytoma diagnosed through endoscopic ultrasound with bronchoscope (EUS-B) fine needle aspiration (FNA) all in the same endoscopic procedure.

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