Publications by authors named "Anooja Jose"
Erdosteine: Reigniting a Thiol Mucolytic for Management of Chronic Obstructive Pulmonary Disease.
J Assoc Physicians India
January 2025
Chronic obstructive pulmonary disease (COPD) is a major health burden globally and in India. Oxidative stress plays a pivotal role in the pathogenesis of COPD, causing mucus hypersecretion, bronchoconstriction, and accelerated lung function decline. An important class of pharmacological agents that are often less discussed are the thiol mucolytic agents, which have a two-pronged effect of serving as both a mucolytic and an antioxidant.
View Article and Find Full Text PDFOlmesartan: 360-degree Perspectives Befitting an Angiotensin Receptor Blocker.
J Assoc Physicians India
December 2024
India has a high burden of hypertension (HTN), which is often poorly controlled, leading to hypertension-mediated organ damage (HMOD). In the management of HTN, angiotensin receptor blockers (ARBs) assume prime importance, being first-line agents for most patient subgroups. Olmesartan is a highly efficacious ARB that demonstrates sustained blood pressure (BP) reduction over 24 hours.
View Article and Find Full Text PDFArticle Synopsis
- SARS-CoV-2, originating in Wuhan in December 2019, causes COVID-19, which was declared a pandemic by the World Health Organization due to its rapid global spread.
- Initial links to the outbreak point to the Huanan seafood market, with bats believed to be a key host for the virus, while the risk of human transmission is heightened by asymptomatic carriers.
- Prevention and precaution are emphasized as essential strategies, alongside ongoing research into treatment and understanding the pandemic's worldwide impact and future challenges.