Evaluation of Photochemistry Reaction Kinetics to Pattern Bioactive Proteins on Hydrogels for Biological Applications.

Bioactive signals play many important roles on cell function and behavior. In most biological studies, soluble biochemical cues such as growth factors or cytokines are added directly into the media to maintain and/or manipulate cell activities . However, these methods cannot accurately mimic certain biological signaling motifs, which are often immobilized to extracellular matrix and also display spatial gradients that are critical for tissue morphology.