Alternative, non-invasive, and non-pharmaceutical options are gaining place in the battle of Alzheimer's Disease treatment control. Lately, the magnetic stimulation of the brain is the most prevalent technique with encouraging results. The aim of this study is to establish any possible change on the Primary Dominant Frequencies (PDF) (range 2-7 Hz) of the affected brain regions in Alzheimer Disease (AD) patients after applying extremely weak Transcranial Magnetic Stimulation.
View Article and Find Full Text PDFMagnetoencephalographic recordings, external picoTesla Transcranial Magnetic Stimulation (pT-TMS) and a double blind experimental design were used for the evaluation of 10 epilepsy patients (three males, seven females). Their ages ranged from 23 to 48 years. Our results showed an enhancement in the 2-7 Hz frequency range in five out of nine patients who had a statistically significant difference (55%).
View Article and Find Full Text PDFWe investigated the beta rhythm in 10 children with autism disorders (six boys and four girls) aged 5-12 (mean± SD: 8.3± 2.1) before and after the application of pico Tesla transcranial magnetic stimulation (pT-TMS) using magnetoencephalography (MEG).
View Article and Find Full Text PDFMEG data for five cerebral palsy patients were taken using a whole-head 122-channel MEG system. An experiment was designed to identify the possible effect of external pico-Tesla weak magnetic fields. The subjects were five male volunteers 17-46 years of age.
View Article and Find Full Text PDFJ Integr Neurosci
April 2018
A 82-year-old male experiencing headaches, dementia, urinary incontinence and gait instability was diagnosed with normal pressure hydrocephalus (NPH) and underwent a resting state magnetoencephalography (MEG) examination. MEG data were recorded in a magnetically shielded room with a whole-head 122 channel biomagnetometer. Following MEG, a ventriculoperitoneal (VP) shunt was placed in his head and greatly improved his symptomatology.
View Article and Find Full Text PDFObjective: the possible diff erences in processing gustatory stimuli in healthy subjects was investigated by magnetoencephalography (meg).
Matherial And Method: meg recordings were evaluated for 10 healthy volunteers (3 men within the age range 20-46 years, 7 women within the age range 10-28 years), with four diff erent gustatory stimuli: sweet, bi" er, sour and salty. Fast fourier transform was performed on meg epochs recorded for the above conditions and the eff ect of each kind of stimuli on alpha rhythm was examined.
Magnetoencephalographic (MEG) recordings from the brain of 10 children with autism (6 boys and 4 girls, with ages range from 5-12 years, mean[Formula: see text][Formula: see text][Formula: see text]SD: 8.3[Formula: see text][Formula: see text][Formula: see text]2.1) were obtained using a whole-head 122-channel MEG system in a magnetically shielded room of low magnetic noise.
View Article and Find Full Text PDFMult Scler Relat Disord
July 2016
Magnetoencephalographic (MEG) recordings of 10 multiple sclerosis (MS) patients (2 men, 8 women, mean 41.3±9.5 years, mean disease duration 12.
View Article and Find Full Text PDFClin Exp Obstet Gynecol
July 2016
This article reports the application of non-linear analysis to biomagnetic signals recorded from fetal growth restriction, fetal brain activity, ovarian lesions, breast lesions, umbilical arteries, uterine myomas, and uterine arteries in a Greek population. The results were correlated with clinical findings. The biomagnetic measurements and the application of non-linear analysis are promising procedures in Obstetrics and Gynecology.
View Article and Find Full Text PDFMagnetoencephalographic (MEG) recordings of the brain in Parkinson's disease were obtained in order to look for possible effect of pico-Tesla transcranial magnetic stimulation (pT-TMS). We found a significant effect of an increase of frequencies in the range of 2-7 Hz across subjects. In addition, we observed the mean peak frequency difference within the 2-7 Hz band towards frequencies of less or equal to those frequencies of the alpha frequency range (8-13 Hz).
View Article and Find Full Text PDFMagnetoencephalography (MEG) is the recording of the magnetic field produced by the flowing of ions in the brain. This article reports our experience in the application of MEG in patients and healthy volunteers in the Greek population. We provide a brief description of our research work.
View Article and Find Full Text PDFJ Theor Biol
January 2016
The aim of this study is to provide information regarding the comparison of a neural model to MEG measurements. Our study population consisted of 10 epileptic patients and 10 normal subjects. The epileptic patients had high MEG amplitudes characterized with θ (4-7 Hz) or δ (2-3 Hz) rhythms and absence of α-rhythm (8-13 Hz).
View Article and Find Full Text PDFWe used a double-blind experimental design to look for an effect of pico-Tesla magnetic stimulation in healthy subjects. Pico-Tesla stimulation is thought to increase the dominant frequency of 2-7 Hz oscillations in the human brain. We used magnetoencephalography to measure resting state brain activity.
View Article and Find Full Text PDFJ Integr Neurosci
September 2014
The purpose of this study was to use magnetoencephalography (MEG) to identify epileptic zones in patients with brain tumors before undergoing tumor surgery. The MEG data were recorded with a 122-channel biomagnetometer. Equivalent current dipoles (ECD) were calculated for epileptic spikes on MEG recordings according to the single dipole model.
View Article and Find Full Text PDFMagnetoencephalography (MEG) recordings were evaluated for 25 healthy female volunteers, in five different gustatory states: normal, sweet, bitter, sour and salty. The study population was divided in two groups according to age: group A (10-19 years old) and group B (20-30 years old). There was a higher count of low frequencies (2 Hz) and a lower count of high frequencies (7 Hz) with increasing age, in all studied states.
View Article and Find Full Text PDFMagnetoencephalographic recordings were evaluated in five different states: normal condition, sweet, bitter, sour, and salt taste. Twenty-eight healthy volunteers, 14 male and 14 female, ranging from 12 to 50 years of age, were included in the study. The results showed that, in the normal condition, as well as in the sweet and the bitter taste, the male volunteers exhibited a higher count of low-frequency than high-frequency channels compared to the femal ones; in the case of the sour taste, there was no clear differentiation between the genders; with the salt taste, the female volunteers exhibited a higher count of low-frequency channels whereas there was no clear differentiation in the number of high frequencies between the gender.
View Article and Find Full Text PDFThe aim of this study is to investigate the electromagnetic sources of epileptic activity in two patients with juvenile myoclonus epilepsy (JME). The first patient was a 22-year old female with JME diagnosis by the age of 17 years old. Her initial EEG recording showed characteristic paroxysmal generalized activity with polyspike-wave complexes.
View Article and Find Full Text PDFThe aim of this study is to assess any cerebral dysfunction in young children, who experienced febrile seizures, by means of magnetoencephalography. Our study population included 15 children (9 boys, 6 girls) within the age range of 2 to 7 years. The magnetoencephalography data were recorded with a 122-channel biomagnetometer.
View Article and Find Full Text PDFMagnetoencephalogram (MEG) recordings of 8 patients with advanced Alzheimer Disease (AD) and 9 normal individuals were obtained with a 122-channel whole head biomagnetometer SQUID (Superconductive Quantum Interference Device) to record the minute magnetic fields generated by the brain. The obtained MEG signals were analyzed using linear signal analysis techniques such as Fourier Transform in order to get the frequency distribution of MEG values. The obtained frequencies from all MEG sensors located outside the scalp of each subject were stored for evaluation.
View Article and Find Full Text PDFJ Integr Neurosci
December 2008
We investigated the localization of current sources in the time and frequency domain from spontaneous MEG data recorded from nine epileptic patients (six females; three males) randomly selected, who had a mean age of 41 years old (range of 17-78 years old), with different types of epilepsy. The MEG data were recorded in a magnetically shielded room with a whole-head 122 channel biomagnetometer. For each MEG spike, we calculated the single Equivalent Current Dipole (ECD) sources at the initial spike peaks with a spherical model.
View Article and Find Full Text PDFObjective: The aim of this study was to investigate the role of biomagnetic activity measurements in detecting prostate malignancies, in differentiating cancerous from benign prostate lesions and in generally improving our understanding of prostate cancer biology.
Methods: Magnetic recordings were obtained from 47 patients with palpable prostate lesions. Twenty-four had prostate carcinoma and 23 benign prostatic hyperplasia (BPH).
Magnetoencephalographic (MEG) recordings of patients with CNS disorders were obtained using a whole-head 122-channel magnetometer SQUID and analyzed using Fourier statistical analysis. External transcranial magnetic stimulation in the order of pico Tesla (pTMS) was applied to the above patients with proper characteristics (magnetic intensity 1-7.5 pT; frequency: 8-13 Hz) which were obtained with MEG recordings prior to pTMS.
View Article and Find Full Text PDFIn this study we examined the dynamic behavior of isolated and non-isolated neural networks with chemical markers that follow a Poisson or Gauss distribution of connectivity. The Poisson distribution shows higher activity in comparison to the Gauss distribution although the latter has more connections that obliterated due to randomness. We examined 57 hematoxylin and eosin stained sections from an equal number of autopsy specimens with a diagnosis of "cerebral matter within normal limits".
View Article and Find Full Text PDFObjectives: Non-linear analysis was applied on MEG signals of Alzheimer Disease (AD) patients in order to investigate the underlying complexity of the brain dynamics.
Materials And Methods: A Single channel SQUID was used to record the MEG signals in 9 AD patients and 5 normal individuals. The magnetic activity, for each patient, was recorded from a total of 64 points of the skull (32 points from each temporal lobe).
The aim of this study is to investigate if there is any nonlinearity in the magnetoencephalographic recordings of patients with multiple sclerosis in comparison with controls in order to find out the differences in the mechanisms underlying their brain waves. Five multiple sclerosis patients and five controls were included in this study. Chaotic activity of multiple sclerosis patients is lower than in the normal brain.
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