Deteriorated abatement of micropollutants in biological activated carbon filters with aged media: Key role of permeability.

Biological activated carbon (BAC) filtration is vital for the abatement of micropollutants in drinking water. However, limited information is available on contaminant removal in BAC filters with aged media (e.g.

ETS1 deficiency in macrophages suppresses colorectal cancer progression by reducing the F4/80+TIM4+ macrophage population.

Tumor-associated macrophages (TAMs) take on pivotal and complex roles in the tumor microenvironment (TME); however, their heterogeneity in the TME remains incompletely understood. ETS proto-oncogene 1 (ETS1) is a transcription factor that is mainly expressed in lymphocytes. However, its expression and immunoregulatory role in colorectal cancer (CRC)-associated macrophages remain unclear.

FSTL3 promotes tumor immune evasion and attenuates response to anti-PD1 therapy by stabilizing c-Myc in colorectal cancer.

Programmed cell death 1 ligand 1 (PDL1)/programmed cell death 1 (PD1) blockade immunotherapy provides a prospective strategy for the treatment of colorectal cancer (CRC), but various constraints on the effectiveness of the treatment are still remaining. As reported in previous studies, follistatin-like 3 (FSTL3) could mediate inflammatory response in macrophages by induction lipid accumulation. Herein, we revealed that FSTL3 were overexpressed in malignant cells in the CRC microenvironment, notably, the expression level of FSTL3 was related to tumor immune evasion and the clinical efficacy of anti-PD1 therapy.

Application of modified receptor model for soil heavy metal sources apportionment: a case study of an industrial city, China.

As we all know, geochemical data usually contain outliers and they are heterogeneous, which will severely affect the use of receptor models based on classical estimates. In this paper, an advanced modified RAPCS-RGWR (robust absolute principal component scores-robust geographically weighted regression) receptor model was introduced to analyze the pollution sources of eight heavy metals (Cd, Hg, As, Pb, Ni, Cu, Zn) in a city of southern China. The results showed that source identification and source apportionment are more consistent by this advanced model even though the soil types and farming patterns are diverse.

Effects of mycorrhizae and water conditions on perennial ryegrass growth in rare earth tailings.

Mycorrhizal symbioses, which include plant roots and arbuscular mycorrhizal fungi (AMF), can significantly enhance plant resistance and promote the absorption of soil nutrients by plants. A greenhouse experiment was conducted to investigate the effects of three AMF species (, and ) on the height, biomass, malondialdehyde (MDA) and proline contents and antioxidant enzyme activities of perennial ryegrass () under different water supply treatments. Potted experimental soil samples were collected from the abandoned rare earth tailings in Ganzhou, Jiangxi.

Loss of Gsdf leads to a dysregulation of Igf2bp3-mediated oocyte development in medaka.

Gonadal soma-derived factor (Gsdf) is a unique TGF-β factor essential for both ovarian and testicular development in Hd-rR medaka (Oryzias latipes). However, the downstream genes regulated by Gsdf signaling remain unknown. Using a high-throughput proteomic approach, we identified a significant increase in the expression of the RNA-binding protein Igf2bp3 in gsdf-deficient ovaries.

Linkage between soil nutrient and microbial characteristic in an opencast mine, China.

Interaction between soil nutrients and microorganisms makes great contributions to soil quality in mining spoils of fragile ecological environment. While this was not very clear in opencast mine area located in western China. Based on an emerging tool of high-throughput sequencing and a comprehensive analysis method, canonical correlation analysis (CCA), the relationship between microorganisms dominant species and soil nutrients in mined areas located in Loess Plateau of China was studied.

Quantitative correlations between soil and plants in reclaimed mining dumps using a coupling coordination degree model.

It is generally accepted that coevolution between soil and plant has great significance for the sustainable development of mining dumps in fragile eco-environment. However, this was not very clear in opencast mine area located in Western China. Based on comprehensive index systems and a combination of subjective and objective weighting method, a coupling coordination degree model, including comprehensive evaluation function, coupling degree and coupling coordination degree, was established to find the 'short plank' of different reclamation patterns and to quantify the status quo of coevolution between soil and plant systems in mined plots.

Microbial response to CaCO application in an acid soil in southern China.

Calcium carbonate (CaCO) application is widely used to ameliorate soil acidification. To counteract soil and bacterial community response to CaCO application in an acidic paddy soil in southern China, a field experiment was conducted with four different dosages of CaCO addition, 0, 2.25, 4.

[Effects of CaCO Application on Soil Microbial Nitrogen Cycle in an Acid Soil].

Soil nitrification and denitrification are important steps in closing the nitrogen cycle. Understanding the effects of CaCO application on the physicochemical properties and nitrogen cycle in acid soil would provide some theoretical and technical information for stable and sustainable utilization of this agricultural soil. In this study, a field trial was conducted in Xiangtan city, Hunan province.