Bryophyllum pinnatum modulation of signaling pathways relevant for preterm labor in human myometrial cells.

Preparations of Bryophyllum pinnatum have been used as a well-tolerated treatment of preterm labor, initially in anthroposophic hospitals and, more recently, also in conventional settings. In vitro studies with human myometrial cells have shown that B. pinnatum leaf press juice inhibits both intracellular Ca signaling and the activation of inflammatory pathways induced by the relevant hormone oxytocin.