Publications by authors named "Annika T Beck"
Article Synopsis
- The Mayo-Baylor RIGHT 10K Study focused on using pharmacogenomics to improve drug prescriptions based on genetic information in a large population.
- Researchers sequenced the DNA of over 10,000 participants to identify genetic variations affecting drug responses, and integrated these findings into electronic health records.
- Results showed that 79% of participants had actionable genetic variants affecting their medication, highlighting the need for a proactive approach to personalized medicine in clinical care.
Background: Prognostic information is key to shared decision-making, particularly in life-limiting illness like advanced chronic kidney disease (CKD).
Objective: To understand the prognostic information preferences expressed by older patients with CKD.
Design And Participants: Qualitative study of 28 consecutively enrolled patients over 65 years of age with non-dialysis dependent CKD stages 3b-5, receiving care in a multi-disciplinary CKD clinic.
Article Synopsis
- The study explores how biobank participants understand pharmacogenomic (PGx) results, specifically regarding drug-gene interactions that affect their health.
- Conducted through focus groups, the research reveals participants' themes around health implications, drugs, and genetics, indicating they generally grasp their PGx results.
- Findings suggest the need for improved communication strategies in PGx disclosure, recognizing participants' understanding while addressing misunderstandings about drug interactions and genetics.
Article Synopsis
- Genomic sequencing is increasing, making it hard to offer genetic counseling to everyone, so a hybrid approach of in-person communication for actionable results and mail for other results is being explored.
- In a study, participants who received neutral genomic screening results by mail reported high satisfaction and generally understood their results, though a few had misunderstandings about their disease risk.
- The study found that receiving neutral results by mail did not lead to distress or negative health behavior changes, but some individuals may still benefit from extra genetic counseling for context regarding their results.
Introduction: Minority communities have had limited access to advances in genomic medicine. Mayo Clinic and Mountain Park Health Center, a Federally Qualified Health Center in Phoenix, Arizona, partnered to assess the feasibility of offering genomic screening to Latino patients receiving care at a community-based health center. We examined primary care provider (PCP) experiences reporting genomic screening results and integrating those results into patient care.
View Article and Find Full Text PDFPurpose: The aim of the study was to characterize experiences of Latino participants receiving genomic screening results.
Methods: Participants were recruited at a federally qualified health center in the USA. In-person, semi-structured interviews were conducted in either Spanish or English by a bilingual, bicultural interviewer.
As applications of genomic sequencing have expanded, offering genetic counseling support to all patients is arguably no longer practical. Additionally, whether individuals desire and value genetic counseling services for genomic screening is unclear. We offered elective genetic counseling to 5110 individuals prior to undergoing sequencing and 2310 participants who received neutral results to assess demand.
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