Targeted metagenomics - Enrichment for enzymes active on sulfated polysaccharides from seaweeds.

Seaweeds (macroalgae) are an attractive resource for diverse microbial- and enzymatic production processes. They are abundant, underutilized, cheap, and rich in carbohydrates, and therefore have the potential to be used as a source of mono- or oligosaccharides, and as substrates for industrial fermentation processes. Many seaweed polysaccharides, including the sulfated polysaccharides ulvan and fucoidan, are however complex and heterogenous in structure, and there are currently few enzymes available to modify them, and understanding of their enzymatic depolymerization remains limited.

[Pediatric sepsis - new national recommendations for recognition and initial treatment].

A task force appointed by the Swedish Society of Pediatric Infectious Diseases developed national treatment recommendations for pediatric sepsis. It is limited to previously healthy children between 28 days (corrected) to 18 years of age and presented as a flow chart. Sepsis should be thought of as a life-threatening organ dysfunction caused by a dysregulated host response to infection.

Education, decision support, feedback and a minor reward: a novel antimicrobial Stewardship intervention in a Swedish paediatric emergency setting.

Sweden enjoys a favourable situation with regard to antimicrobial resistance. However, healthcare costs are expected to increase exponentially, along with increased morbidity and mortality, due to the emergence of resistant bacterial strains. Our aim was to design an antimicrobial stewardship programme suitable for Scandinavian settings.