Synopsis of recent research by authors named "Annika Husken"
- Annika Husken's research primarily focuses on innovative bioconjugation strategies and enzyme specificity profiling, exploring the connection between amino acids and protein modification techniques.
- A significant study details the rapid cleavage of an unnatural amino acid to reveal a highly reactive α-oxo aldehyde, facilitating site-specific protein modifications within mere minutes through SPANC ligation methods.
- Additionally, Husken developed a multiplexed LC-MS/MS assay named HAMA, enabling efficient profiling of adenylate-forming enzymes against multiple competing substrates, moving beyond traditional, single-substrate assays to better reflect cellular competition.
