A new class of anti-biofilm compounds possessing 1,4-disubstituted-(1H)-1,2,3-triazolic cores was designed. Their efficient synthesis was performed by means of click chemistry through 1,3-dipolar cycloadditions. Two compounds were found to act as specific anti-biofilm agents against a gram negative species.
View Article and Find Full Text PDFIn France, MSW incineration bottom ash disposal calls for physico-chemical tests and depending on the results the bottom ashes are sorted into different classes allowing the reuse or not. However this study shows that there is no direct correlation between the physico-chemical testings, like leaching, soluble fraction and heavy metal content, and the environmental impact, in terms of biological toxicity. Based on the results of several ecotoxicity testings and their biotest response we define an "ecotoxicity index" and demonstrate there is a correlation between the carboxylic acids amount and the ecotoxicologic index for the bottom ashes.
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