What is the current state of precision rehabilitation? Protocol for a scoping study with a consultation phase.

Introduction: Precision health can be described as the right intervention, at the right time, for the right person, with a focus on monitoring and maintaining health in a longitudinal approach. Despite an increasing focus on precision approaches in medicine, their application in a rehabilitation context remains unexplored. As such, a greater understanding of the current state of the literature is required, in combination with clinician, researcher and healthcare manager perspectives regarding barriers and facilitators to the practical implementation of precision rehabilitation in clinical practice.

Locomotion Efficiency in Children With Cerebral Palsy Experiencing Limited Gross Motor Function: Walking Versus Cycling.

Purpose: This study compares cycling and walking efficiency, and energy expenditure in children with bilateral spastic cerebral palsy (CP). In children with CP, locomotion with body weight support aids such as a tricycle is a potential alternative for less exhausting movements.

Methods: Nine children with CP traveled at comfortable speed for 6 minutes by cycling and walking.

Running capacity in children with bilateral cerebral palsy: What are the biomechanical and neuromotor differences between runners and walkers?

Background: Running is a high-level locomotor activity requiring more from joints, muscles and a more complex interaction of the neuromuscular system than walking. High-level locomotor activity has the potential to shed light on motor function deficits that lower-level activity does not reveal. Therefore, the study aimed to compare biomechanical and neuromotor function between a group of children with bilateral cerebral palsy who are able and unable to run.

How many observations in the reference dataset are required to compute a consistent Gait Deviation Index & Gait Profile Score?

Background: The Gait Deviation Index (GDI) and the Gait Profile Score (GPS) are the most used scores to sum up gait deviations and are used as primary outcomes in many clinical studies. They are considered as equivalent scores. The computation of these scores is based on a reference dataset but often no description is provided.

What can we learn from the relationship between gait deviations and clinical impairments when comparing two databases?

Background: Several previous studies have tried to determine the relationship between gait and clinical impairments in children with Cerebral Palsy (CP). The heterogeneity of the population and the methodology used could explain the discrepancy within the results. Recently, Papageorgiou et al.

Effect of power training on locomotion capacities in children with cerebral palsy with GMFCS level III-IV.

Purpose: Power training (PT) is a promising training modality to improve functional abilities in children with cerebral palsy (CP). This study aimed to implement PT in an adapted school and to assess its effect on locomotion capacities in children with Gross Motor Function Classification System (GMFCS) level III-IV.

Materials And Methods: Nine children with CP (GMFCS level III-IV) were trained three times/week for 12 weeks.

Are Clinical Impairments Related to Kinematic Gait Variability in Children and Young Adults With Cerebral Palsy?

Intrinsic gait variability (GV), i.e., fluctuations in the regularity of gait patterns between repetitive cycles, is inherent to the sensorimotor system and influenced by factors such as age and pathology.

Static Postural Control Deficits in Adults with Myotonic Dystrophy Type 1, Steinert Disease.

Background: Myotonic dystrophy type 1 (DM1) is characterized by progressive and predominantly distal muscle atrophy and myotonia. Gait and balance impairments, resulting in falls, are frequently reported in this population. However, the extent to which individuals with DM1 rely more on a specific sensory system for balance than asymptomatic individuals (AI) is unknown.

Short Walking Exercise Leads to Gait Changes and Muscle Fatigue in Children With Cerebral Palsy Who Walk With Jump Gait.

Objective: The aim of this study was to evaluate kinematic changes and muscle fatigue in jump gait during a walking exercise and the relationship between kinematic changes and muscle fatigue and strength.

Design: This preliminary study included 10 children with cerebral palsy who walk with jump gait. Hip and knee maximal isometric muscle strength were measured using a dynamometer.

Relationship between lower limb strength and walking capacities in children with spastic bilateral cerebral palsy.

Purpose: Evaluate the relationship between different walking capacities and muscle strength in children with bilateral cerebral palsy (BCP) and assess these relationships in stronger and weaker children.

Materials And Methods: Thirty-two children with spastic BCP were included. All participants walked under three speed conditions: comfortable, fast, and for a longer period (6 min).

Muscle fatigue during a short walking exercise in children with cerebral palsy who walk in a crouch gait.

Background: A deterioration of crouch gait was found in a group of children with cerebral palsy (CP) after a short walking exercise. The increased knee flexion reported after a continuous walk could be related with muscle fatigue and muscle strength.

Aim: Does muscle fatigue appears at the end of a walking exercise in children with CP who walk in a crouch gait?

Methods: Eleven children with cerebral palsy (GMFCS I to III) who walk in a crouch gait were included.

Lower limb extension is improved in fast walking condition in children who walk in crouch gait.

The strategies for walking fast have never been reported in children with cerebral palsy who walk in crouch gait. This study aimed to assess to what extent children who walk in crouch gait are able to increase their gait speed and to report the corresponding three-dimensional kinematic adaptations. Eleven children and adolescents (aged between 7 and 17years) with bilateral cerebral palsy, who walk in crouch gait, were asked to walk at their self-selected comfortable speed and then as fast as possible without running.

Static Postural Control in Youth With Osteogenesis Imperfecta Type I.

Objectives: To assess static postural control in eyes-open and eyes-closed conditions in individuals with osteogenesis imperfecta (OI) type I as compared with typically developing (TD) individuals and to explore the relation between postural control and lower limb muscle function.

Design: Cross-sectional study.

Setting: Outpatient department of a pediatric orthopedic hospital.

Impact of a short walking exercise on gait kinematics in children with cerebral palsy who walk in a crouch gait.

Background: Crouch gait results in an increase of the joint stress due to an excessive knee flexion. Daily walking exercises, even when performed at a self-selected speed, may result in a decrease of the extensor muscle strength which could lead to a more severe crouch gait pattern. The aim of this study was to assess the impact of a short walking exercise on gait kinematics in children with cerebral palsy who walk with a crouch gait.

Gross Motor Function Measure Evolution Ratio: Use as a Control for Natural Progression in Cerebral Palsy.

Objective: To develop a new way to interpret Gross Motor Function Measure (GMFM-66) score improvement in studies conducted without control groups in children with cerebral palsy (CP).

Design: The curves, which describe the pattern of motor development according to the children's Gross Motor Function Classification System level, were used as historical control to define the GMFM-66 expected natural evolution in children with CP. These curves have been modeled and generalized to fit the curve to particular children characteristics.

The functional muscle-bone unit in patients with osteogenesis imperfecta type I.

Context: Osteogenesis imperfecta (OI) type I is a heritable bone fragility disorder that is caused by mutations affecting collagen type I. We recently showed that patients with OI type I frequently have muscle weakness. As muscle force and bone mass are usually closely related, we hypothesized that muscle weakness in OI type I could contribute to increase bone mass deficit in the lower extremities.

Muscle anatomy and dynamic muscle function in osteogenesis imperfecta type I.

Context: Results of previous studies suggested that children and adolescents with osteogenesis imperfecta (OI) type I have a muscle force deficit. However, muscle function has only been assessed by static isometric force tests and not in more natural conditions such as dynamic force and power tests.

Objective: The purpose of this study was to assess lower extremity dynamic muscle function and muscle anatomy in OI type I.