transformants expressing oxacillinases and metallo-β-lactamases that confer resistance to meropenem: new tools for anti- drug development and AMR preparedness.

Antimicrobial resistance (AMR) in is an unmet medical need. Multiple drug-resistant/extremely drug-resistant strains of do not display growth well in models, and consequently, their response to antibacterial therapy is inconsistent. We addressed this issue by engineering carbapenem resistance motifs into the highly virulent genetic background of AB5075.