Non-Wilson's Disease-Associated Hypoceruloplasminemia.

Introduction And Aim: Low serum ceruloplasmin levels can occur in patients without Wilson's disease (WD) liver disorders. When present, extensive, costly, and potentially harmful additional investigations for WD may be undertaken. The purpose of this study was to document the prevalence of low serum ceruloplasmin levels in adult patients without WD and describe the features commonly associated with this finding.

Predicting Pre-transplant Abstinence in Patients with Alcohol-Induced Liver Disease.

Background: Some patients with alcohol-induced liver failure will succumb to their disease prior to demonstrating compliance with the six months abstinence rule for liver transplantation.

Purpose: The purpose of this study was to determine whether a patient's self-reported, longest period of abstinence predicts subsequent abstinence.

Methods: Adult patients (n=63) with alcohol-induced liver disease were asked to recall their longest period of abstinence prior to their initial hepatology visit.

Predictors of Alcohol Relapse Following Liver Transplantation for Alcohol-Induced Liver Failure. Consideration of "A-D" Selection Criteria.

Demonstrated abstinence from alcohol for over six months and successful completion of a formal alcohol addictions program are two commonly employed criteria for determining whether an alcoholic patient with liver failure should proceed to liver transplantation. In this systematic review of the medical literature, we review the justification for these criteria and consider other variables that have also been reported to be of predictive value. While abstinence from alcohol for over six months is supported by the medical literature, data are more limited regarding the value of formal alcohol addictions program as selection criteria for proceeding towards liver transplantation.

The impact of child restraint legislation on the incidence of severe paediatric injury in Chile.

Background: The objective of this study is to determine the association between Chile's 2005 child restraint legislation (CRL) and the incidence of severe paediatric motor vehicle-related injury.

Methods: We analysed motor vehicle injury data from Chile's Road Safety Commission from 2000 to 2012 to determine the association between Chile's 2005 CRL and severe paediatric injury. Using Poisson time-series models we assessed the effect of the law on two outcome variables: (1) severely injured children per vehicle fleet; and (2) severely injured children per population.